| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): The Israeli researchers and @IsraelMOH have done extraordinary work of rapidly accruing and publishing their unique data, teaching us about the impact of vaccination and fading immunity. They've not been adequately recognized for their contributions to date. → https://twitter.com/EricTopol/status/1451306512442277914 | 00:07 |
|---|---|---|
| Brainstorm | Updates for Dominican Rep.: +889 cases (now 373929), +2 deaths (now 4097), +4881 tests (now 2.2 million) since 2 hours ago — Qatar: +106 cases (now 238271), +5191 tests (now 2.8 million) since a day ago — Kuwait: +25 cases (now 412449), +1 deaths (now 2459), +18043 tests (now 4.7 million) since a day ago | 00:09 |
| LjL | "Also, T cells betray you to cause severe disease" what? | 00:15 |
| LjL | https://mobile.twitter.com/fitterhappierAJ/status/1451159562514583553 | 00:16 |
| Brainstorm | New from The Lancet (Online): [Correspondence] Fertility rates and birth outcomes after ChAdOx1 nCoV-19 (AZD1222) vaccination: Fears of adverse effects of COVID-19 vaccination on fertility have affected vaccine uptake in some communities. Despite the absence of supporting evidence for such [... want %more?] → https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)02282-0/fulltext | 00:39 |
| de-facto | .title https://www.medrxiv.org/content/10.1101/2021.10.07.21264626v1 | 00:56 |
| Brainstorm | de-facto: From www.medrxiv.org: Protection Across Age Groups of BNT162b2 Vaccine Booster against Covid-19 | medRxiv | 00:56 |
| Brainstorm | Updates for Argentina: +1541 cases (now 5.3 million), +26 deaths (now 115796), +53251 tests (now 24.7 million) since a day ago — Isle of Man: +114 cases (now 8931), +3451 tests (now 128771) since 23 hours ago | 01:05 |
| Brainstorm | New from COVID tweets: Retraction Watch (@RetractionWatch): Our list of retracted COVID-19 papers is up to 183. For context and denominators, please see the page. retractionwatch.com/retracted-coro… pic.twitter.com/yLCVSULTXb → https://twitter.com/RetractionWatch/status/1451319275935907841 | 01:10 |
| Brainstorm | New from r/WorldNews: worldnews: Pfizer has secret government contracts for COVID vaccines: Advocacy group says company puts profits over public health and reveals seven of its contracts are worth $5BILLION → https://old.reddit.com/r/worldnews/comments/qd3o23/pfizer_has_secret_government_contracts_for_covid/ | 01:20 |
| Brainstorm | Updates for Bulgaria: +4816 cases (now 559893), +120 deaths (now 22839), +47366 tests (now 5.2 million) since a day ago — Faroe Is.: +60 cases (now 1410), +4000 tests (now 455000) since 3 days ago — Jordan: +1473 cases (now 847506), +15 deaths (now 10918), +27834 tests (now 10.7 million) since a day ago [... want %more?] | 01:36 |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): An outstanding new review of the immune response to #SARSCoV2 infection and covid vaccines, with attention to reinfection, duration, and mechanisms thelancet.com/journals/lanre… @LancetRespirMed by @GC_Milne and colleagues pic.twitter.com/XifpCrHDGD → https://twitter.com/EricTopol/status/1451334518162354178 | 01:51 |
| Brainstorm | Updates for Uruguay: +178 cases (now 391700), +10146 tests (now 3.7 million) since 23 hours ago — Bahrain: +59 cases (now 276395), +16685 tests (now 6.8 million) since a day ago — Zimbabwe: +53 cases (now 132540), +2 deaths (now 4662), +4975 tests (now 1.5 million) since 4 hours ago | 02:01 |
| Brainstorm | New from Johnson&Johnson: (news): U.S. CDC Advisory Committee Unanimously Recommends Johnson & Johnson COVID-19 Vaccine as a Booster for All Eligible Individuals Who Receive Authorized [... want %more?] → https://www.jnj.com/u-s-cdc-advisory-committee-unanimously-recommends-johnson-johnson-covid-19-vaccine-as-a-booster-for-all-eligible-individuals-who-receive-authorized-covid-19-vaccines | 02:02 |
| Brainstorm | Updates for United Kingdom: +51764 cases (now 8.7 million), +118 deaths (now 139562) since 23 hours ago | 02:39 |
| Brainstorm | Updates for Barbados: +392 cases (now 14326), +1 deaths (now 124), +2830 tests (now 367365) since 23 hours ago — Mali: +43 cases (now 15741), +1359 tests (now 443473) since 5 hours ago — S. Sudan: +9 cases (now 12279), +1293 tests (now 245170) since 23 hours ago | 03:03 |
| Brainstorm | New from r/Science: science: Covid-19 Vaccination during Pregnancy and First-Trimester Miscarriage → https://old.reddit.com/r/science/comments/qd4njw/covid19_vaccination_during_pregnancy_and/ | 03:04 |
| Brainstorm | Updates for St. Vin. and Gren.: +57 cases (now 4786), +406 tests (now 84787) since a day ago — Netherlands: +5207 cases (now 2.1 million) since 23 hours ago | 03:34 |
| Brainstorm | Updates for Belize: +296 cases (now 25244), +2 deaths (now 473), +2556 tests (now 295778) since a day ago — Panama: +205 cases (now 471060), +3 deaths (now 7303), +6869 tests (now 4.0 million) since a day ago | 03:59 |
| Brainstorm | Updates for South Korea: +1440 cases (now 348969), +16 deaths (now 2725), +45380 tests (now 15.4 million) since a day ago — Bolivia: +536 cases (now 508702), +4 deaths (now 18891), +6262 tests (now 2.5 million) since a day ago — New Zealand: +133 cases (now 5449), +27829 tests (now 3.9 million) since a day ago | 04:37 |
| Brainstorm | New from r/WorldNews: worldnews: The WHO said Thursday that 80,000 to 180,000 health care workers may have been killed by Covid-19 up to May this year, insisting they must be prioritized for vaccination → https://old.reddit.com/r/worldnews/comments/qd7myv/the_who_said_thursday_that_80000_to_180000_health/ | 05:10 |
| Brainstorm | New from COVID tweets: Michael Lin, PhD-MD 🧬 (@michaelzlin): @US_FDA Happy to add one more. It's now officially recommended by CDC too.Starting tomorrow, 22 Oct 2021, if you're a #JnJer, you can finally walk into any vaccination site and ask for a Moderna or Pfizer boost. And you can do it loudly and proudly [... want %more?] → https://twitter.com/michaelzlin/status/1451389464467496962 | 05:30 |
| Brainstorm | Updates for Belgium: +6239 cases (now 1.3 million), +19 deaths (now 25835) since a day ago | 05:39 |
| LjL | %title https://www.cnbc.com/2021/10/21/putin-to-order-russians-to-stop-work-for-a-week-as-covid-deaths-soar.html | 05:52 |
| Brainstorm | LjL: From www.cnbc.com: Putin to order Russians to stop work for a week as Covid deaths soar | 05:52 |
| Brainstorm | New from COVID tweets: Infection Prevention RN (@RnInfection): @michaelzlin @US_FDA So there will be many young males that will opt for another J&J, which you had said to me a few days ago, 2 J&J is equivalent to the original series of Pfizer from a protection standpoint. So let's try avoid painting J&J as such a [... want %more?] → https://twitter.com/RnInfection/status/1451394822439383041 | 06:12 |
| LjL | wow. deaths in russia are growing like crazy. and they kinda never went down to near zero unlike other countries' "waves" | 06:14 |
| -RSSBot[LjLmatrix- Zotero / COVID links Group / Top-Level Items: Immunogenicity and efficacy of heterologous ChadOx1/BNT162b2 vaccination ( https://www.zotero.org/groups/covid_links/items/7ST5VIXC ) | 06:18 | |
| Brainstorm | Updates for India: +15786 cases (now 34.1 million), +1324263 tests (now 597.1 million) since 23 hours ago — Germany: +17506 cases (now 4.4 million) since 20 hours ago | 06:41 |
| Brainstorm | New from Reddit (test): nCoV: GOP investigation 'proves' COVID leaked from Wuhan lab: report | links to .gov report and its addendum in comments | 21OCT21 → https://old.reddit.com/r/nCoV/comments/qd90ed/gop_investigation_proves_covid_leaked_from_wuhan/ | 06:43 |
| Brainstorm | New from The Indian Express: World: New Zealand sets 90% vaccine target to end lockdowns and reopen → https://indianexpress.com/article/world/new-zealand-sets-90-vaccine-target-to-end-lockdowns-and-reopen/ | 06:53 |
| Brainstorm | Updates for Inner Mongolia, China: +16 cases (now 451) since 23 hours ago — Gansu, China: +9 cases (now 218) since 23 hours ago — Lombardy, Italy: +383 cases (now 890161), +1 deaths (now 34131) since 23 hours ago — Qinghai, China: +1 cases (now 19) since a month ago | 07:31 |
| sKep | %cases russia | 07:33 |
| Brainstorm | sKep: Russia has had 8.1 million confirmed cases (5.5% of all people) and 227389 deaths (2.8% of cases) as of 19 hours ago. 202.1 million tests were done (4.0% positive). 52.0 million were vaccinated (35.4%). +36339 cases, +1036 deaths, +577413 vaccines since a day ago. See https://offloop.net/covid19/?default=Russia | 07:33 |
| Brainstorm | sKep: If you know of an official or otherwise good site for data about Russia, with a reasonably short URL, please %tell LjL about it. | 07:33 |
| sKep | %cases brazil | 07:34 |
| Brainstorm | sKep: Brazil has had 21.7 million confirmed cases (10.3% of all people) and 604764 deaths (2.8% of cases) as of 5 hours ago. 63.8 million tests were done (34.0% positive). 156.5 million were vaccinated (74.1%). +16852 cases, +451 deaths since 23 hours ago. See https://offloop.net/covid19/?default=Brazil | 07:34 |
| Brainstorm | sKep: If you know of an official or otherwise good site for data about Brazil, with a reasonably short URL, please %tell LjL about it. | 07:34 |
| sdfgsdfgs | US chart is slowing down, are we in for a plot twist for north america as well :'D | 07:56 |
| Brainstorm | New from COVID tweets: Eric Feigl-Ding (@DrEricDing): BEST BOOSTER? Mix it up — but depends which you had first. Switching vaccine for the booster seems to be the best—Pfizer to Moderna booster, Moderna to Pfizer for booster, and J&J should switch to Moderna / Pfizer booster. HT to @ScientistSwanda. #COVID19 [... want %more?] → https://twitter.com/DrEricDing/status/1451418802416197633 | 08:05 |
| stompykins | %cases usa | 08:06 |
| Brainstorm | Updates for Kyrgyzstan: +125 cases (now 180348), +4 deaths (now 2647), +3435 tests (now 1.8 million) since a day ago | 08:06 |
| Brainstorm | stompykins: United States has had 46.2 million confirmed cases (14.0% of all people) and 753747 deaths (1.6% of cases) as of 4 hours ago. 677.2 million tests were done (6.8% positive). 219.4 million were vaccinated (66.6%). +107902 cases, +3367 deaths since 23 hours ago. See https://offloop.net/covid19/?default=United%20States | 08:06 |
| Brainstorm | stompykins: If you know of an official or otherwise good site for data about United States, with a reasonably short URL, please %tell LjL about it. | 08:06 |
| Brainstorm | New from r/Coronavirus: Daily Discussion Thread | October 22, 2021: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/qdbbe0/daily_discussion_thread_october_22_2021/ | 09:07 |
| Brainstorm | Updates for Georgia: +4155 cases (now 684337), +40 deaths (now 9657), +49960 tests (now 9.8 million) since a day ago — Czechia: +3638 cases (now 1.7 million), +6 deaths (now 30593), +177489 tests (now 39.7 million) since 21 hours ago | 09:35 |
| Brainstorm | Updates for Lithuania: +3016 cases (now 382454), +27 deaths (now 5571), +26493 tests (now 5.4 million) since 23 hours ago — Hungary: +2548 cases (now 843825), +24 deaths (now 30492), +19830 tests (now 7.2 million) since 23 hours ago | 10:00 |
| Brainstorm | Updates for Austria: +3582 cases (now 791226), +13 deaths (now 11233), +284844 tests (now 94.3 million) since 23 hours ago — Germany: +7590 cases (now 4.4 million) since 16 hours ago | 10:37 |
| Brainstorm | New from StatNews: Opinion: Don’t give Covid-19 long-haulers the silent treatment: The plight of people with ME/CFS and fibromyalgia — being dismissed and silenced — must not be repeated for people with long Covid. @WesElyMD @Survivor_Corps @patientled → https://www.statnews.com/2021/10/22/dont-give-covid-19-long-haulers-the-silent-treatment/ | 10:55 |
| Brainstorm | Updates for Armenia: +2146 cases (now 291052), +42 deaths (now 5944), +18598 tests (now 2.0 million) since a day ago — Estonia: +1323 cases (now 178610), +8458 tests (now 2.1 million) since 19 hours ago | 11:02 |
| Brainstorm | New from COVID tweets: Tom Wenseleers (@TWenseleers): And to clarify: this was 95.6% efficacy against symptomatic disease in the 3-dose arm vs a 2-dose vaccinated population. This would imply ca 99% efficacy in comparison to unvaccinated. Roll out those 3d doses I would say! More details in thread below. [... want %more?] → https://twitter.com/TWenseleers/status/1451473190790877222 | 11:06 |
| Brainstorm | New from The Indian Express: World: Thailand to allow quarantine-free travel from 46 countries, PM says → https://indianexpress.com/article/world/thailand-quarantine-free-travel-tourism-7584825/ | 11:17 |
| Brainstorm | New from COVID tweets: Tom Wenseleers (@TWenseleers): "Per 100.000 gevaccineerde inwoners tussen 18 en 64 jaar in Vlaanderen waren er vorige week 0,9 opnames. Bij niet-gevaccineerden in dezelfde groep waren dat er 9,8": 10 keer meer dus... Laat je dus vaccineren! demorgen.be/ts-b1cbd29b via @demorgen pic.twitter.com/dWXxszUXBY → https://twitter.com/TWenseleers/status/1451477905914187800 | 11:27 |
| Brainstorm | New from r/WorldNews: worldnews: Regional quarantine facility well under way at Wellcamp → https://old.reddit.com/r/worldnews/comments/qdd465/regional_quarantine_facility_well_under_way_at/ | 11:37 |
| Brainstorm | Updates for Poland: +5716 cases (now 3.0 million), +59 deaths (now 76359), +49537 tests (now 21.8 million) since a day ago — Slovakia: +3470 cases (now 449775), +3 deaths (now 12886), +14282 tests (now 3.8 million) since a day ago | 11:39 |
| Brainstorm | New from r/WorldNews: worldnews: 'The UK really is in trouble': Doctors warn of a dire Covid crisis as officials reject restrictions → https://old.reddit.com/r/worldnews/comments/qdd5o9/the_uk_really_is_in_trouble_doctors_warn_of_a/ | 11:48 |
| Brainstorm | Updates for Finland: +449 cases (now 153156), +4 deaths (now 1139), +11695 tests (now 7.4 million) since 22 hours ago | 12:04 |
| Brainstorm | New from r/WorldNews: worldnews: Lithuania's largest news outlets will remove public comments from their websites to combat COVID-19 misinformation → https://old.reddit.com/r/worldnews/comments/qddfrj/lithuanias_largest_news_outlets_will_remove/ | 12:08 |
| Brainstorm | New from r/WorldNews: worldnews: Melbourne reopens as world's most locked-down city eases pandemic restrictions → https://old.reddit.com/r/worldnews/comments/qddz6w/melbourne_reopens_as_worlds_most_lockeddown_city/ | 12:39 |
| Brainstorm | New from COVID tweets: Tom Wenseleers (@TWenseleers): Een goede review over de effectiviteit van de vaccins voor verschillende eindpunten (infectie, hospitalisatie, overlijden) door @IVACtweets kan je hier vinden: view-hub.org/sites/default/… pic.twitter.com/Wfmg8q1czE → https://twitter.com/TWenseleers/status/1451502631575343106 | 13:00 |
| Brainstorm | Updates for Indonesia: +760 cases (now 4.2 million), +33 deaths (now 143153), +250740 tests (now 44.6 million) since 23 hours ago — Nepal: +574 cases (now 808096), +11 deaths (now 11337), +7253 tests (now 4.4 million) since 23 hours ago — Laos: +520 cases (now 34518), +5580 tests (now 586755) since 23 hours ago — Senegal: +4 cases (now 73880), +1197 tests (now 828345) since 23 hours ago | 13:07 |
| Brainstorm | New from COVID tweets: Tom Wenseleers (@TWenseleers): *96% in het beschermen tegen symptomatische ziekte tov dubbel gevaccineerden & 98-99% tov niet gevaccineerden → https://twitter.com/TWenseleers/status/1451503429956800526 | 13:11 |
| ZdrytchX | .cases melbourne | 13:26 |
| Brainstorm | ZdrytchX: Sorry, melbourne not found. Either there aren't cases, or it's under a different name. | 13:27 |
| ZdrytchX | .cases victoria | 13:27 |
| Brainstorm | ZdrytchX: Victoria, Australia has had 75340 confirmed cases (1.1% of all people) and 1021 deaths (1.4% of cases) as of 5 hours ago. +2189 cases, +16 deaths since 23 hours ago. See https://offloop.net/covid19/?default=Victoria | 13:27 |
| Brainstorm | ZdrytchX: If you know of an official or otherwise good site for data about Victoria, with a reasonably short URL, please %tell LjL about it. | 13:27 |
| ZdrytchX | .cases new york | 13:27 |
| Brainstorm | ZdrytchX: New York, United States has had 2.5 million confirmed cases (12.7% of all people) and 56130 deaths (2.2% of cases) as of 5 hours ago. 6.9 million tests were done (36.6% positive). +4363 cases, +53 deaths since 23 hours ago. See https://offloop.net/covid19/?default=New%20York | 13:27 |
| Brainstorm | ZdrytchX: If you know of an official or otherwise good site for data about New York, with a reasonably short URL, please %tell LjL about it. | 13:28 |
| Brainstorm | New from ECDC: Data on the daily number of new reported COVID-19 cases and deaths by EU/EEA country: The downloadable data file is updated daily and contains the latest available public data on COVID-19. Each row/entry contains the number of new cases and deaths reported per day and [... want %more?] → https://www.ecdc.europa.eu/en/publications-data/data-daily-new-cases-covid-19-eueea-country | 14:03 |
| Brainstorm | Updates for Latvia: +3133 cases (now 197389), +25 deaths (now 2992), +21566 tests (now 4.8 million) since a day ago — Switzerland: +1285 cases (now 862408), +2 deaths (now 11193), +26791 tests (now 11.5 million) since 21 hours ago — Gibraltar: +18 cases (now 5842), +1092 tests (now 379429) since 23 hours ago | 14:34 |
| Brainstorm | New from BBC Health: Prepare to trigger Covid Plan B curbs, say scientists: Advisors say early action could save later, tougher measures to stop the spread of Covid. → https://www.bbc.co.uk/news/health-59011321 | 14:45 |
| Brainstorm | New from BMJ: New plan for supporting general practice in England: General practice is the foundation of the NHS, but these foundations are creaking. GP consultation numbers are now higher than before the pandemic.1 Yet the number of permanent, fully qualified GPs... → http://feeds.bmj.com/~r/bmj/recent/~3/IaC5liDBBYE/bmj.n2585.short | 15:06 |
| Brainstorm | Updates for Romania: +15410 cases (now 1.5 million), +357 deaths (now 43844), +66076 tests (now 14.2 million) since a day ago — Brunei: +130 cases (now 11672), +4683 tests (now 465058) since a day ago | 15:11 |
| Brainstorm | New from r/Science: science: COVID reinfections likely within one or two years, models propose. Estimates based on viral evolution forecast a 50% risk 17 months after a first infection without measures such as masking and vaccination. → https://old.reddit.com/r/science/comments/qdg815/covid_reinfections_likely_within_one_or_two_years/ | 15:17 |
| Brainstorm | Updates for Belarus: +2082 cases (now 582111), +16 deaths (now 4482), +42506 tests (now 9.3 million) since a day ago — UAE: +88 cases (now 739106), +2 deaths (now 2128), +279134 tests (now 90.7 million) since a day ago — United Kingdom: +51716 cases (now 8.7 million) since 21 hours ago | 15:36 |
| Brainstorm | New from COVID tweets: Brian Hjelle, virologist (@hjelle_brian): Disruption of blood brain barrier thru destruction of endothelial cells, does that underlie COVID brain pathology? Fascinating if so.nature.com/articles/s4159… → https://twitter.com/hjelle_brian/status/1451540483105181697 | 15:38 |
| Brainstorm | New from COVID tweets: Brian Hjelle, virologist (@hjelle_brian): We'll see if AY.4 can manage more'n a slow crawl to greatness, arising in a sea of delta immunity. BTW, why is a well-vaxed wealthy mid-sized country spawning variants?Oh yeah, Boris.ophthalmologytimes.com/view/covid-19-… → https://twitter.com/hjelle_brian/status/1451544686091403268 | 15:49 |
| Brainstorm | New from StatNews: Pharma: STAT+: Pharmalittle: Four Democratic senators may delay Medicare drug price reform; Western Covid vaccine stockpiles to hit 600M doses by year’s end → https://www.statnews.com/pharmalot/2021/10/22/covid19-vaccine-medicare-insulin-abortion/ | 15:59 |
| Brainstorm | Updates for Uganda: +111 cases (now 125537), +2 deaths (now 3194), +7042 tests (now 1.8 million) since 18 hours ago — Saudi Arabia: +51 cases (now 548162), +1 deaths (now 8774), +46630 tests (now 30.0 million) since 23 hours ago | 16:01 |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): In over 2200 children ages 5-11, a placebo-controlled trial of a dose of 10 μg, 1/3 of adults, showed 90.7% efficacy of Pfizer's vaccine (3 cases in vaccine, 16 in placebo)wsj.com/articles/fda-r… @loftus @JaredSHopkins pic.twitter.com/KdWjPwiGOJ → https://twitter.com/EricTopol/status/1451550539200696320 | 16:10 |
| Brainstorm | New from The Indian Express: World: Pfizer says Covid-19 vaccine more than 90% effective in kids → https://indianexpress.com/article/world/pfizer-covid-19-vaccine-90-effective-kids-7585405/ | 16:20 |
| Brainstorm | Updates for Canada: +2916 cases (now 1.7 million), +24 deaths (now 28729) since 21 hours ago — Qatar: +88 cases (now 238359), +5261 tests (now 2.8 million) since 16 hours ago — Zambia: +21 cases (now 209610), +5020 tests (now 2.6 million) since a day ago — Switzerland: +3 cases (now 862411), +27011 vaccines (now 5.7 million) since 2 hours ago | 16:38 |
| de-facto | Russia got 2021-10-01: 23953 cases and 2021-10-18: 33434 cases meaning 9481 cases in 18 days ~527 cases *increase* per daily new infections | 17:01 |
| Brainstorm | Updates for Germany: +15757 cases (now 4.5 million), +77 deaths (now 95794) since 23 hours ago — Chile: +2004 cases (now 1.7 million), +136077 tests (now 23.0 million) since 22 hours ago — Jordan: +1494 cases (now 849000), +12 deaths (now 10930), +32094 tests (now 10.7 million) since 15 hours ago — India: +5759 cases (now 34.1 million), +85 deaths (now 453090) since 23 hours ago | 17:03 |
| de-facto | Russia got 2021-10-01: 875 deaths and 2021-10-18: 981 deaths meaning 106 deaths in 18 days ~6 deaths *increase* per daily fatal outcomes | 17:04 |
| de-facto | with cases and deaths i mean daily new (the rate of increase for absolute numbers), hence first time derivative of cumulative numbers | 17:05 |
| de-facto | .title https://www.rt.com/russia/537965-russia-announces-covid-holidays/ | 17:07 |
| Brainstorm | de-facto: From www.rt.com: Russia announces fresh national ‘non-working week’ as country reports record number of deaths from Covid-19 since pandemic began — RT Russia & Former Soviet Union | 17:07 |
| de-facto | hopefully they can stop the increase and get it under control again, its of essential importance that more Russians protect themselves by vaccination | 17:08 |
| Brainstorm | New from ClinicalTrials.gov: Integrative Treatment Methods in COVID-19: Conditions : COVID-19; Patient Experience; Health Attitude → https://clinicaltrials.gov/ct2/show/NCT05089578 | 17:23 |
| Brainstorm | New from ClinicalTrials.gov: (news): Ozone Plasma on Lung Function and Inflammatory Parameters in Pulmonary Sequelae Associated With Coronavirus 19 Infection → https://clinicaltrials.gov/ct2/show/NCT05089305 | 17:34 |
| Brainstorm | Updates for Netherlands: +5903 cases (now 2.1 million), +11 deaths (now 18727) since 23 hours ago | 17:40 |
| Brainstorm | New from ClinicalTrials.gov: (news): The Practice of Providing Palliative Care in the Situation of the COVID-19 Pandemic in the Perspective of Physicians and Nurses - Survey Study (PEOpLe-C19-EN Study) → https://clinicaltrials.gov/ct2/show/NCT05089032 | 17:44 |
| Brainstorm | Updates for United Kingdom: +48728 cases (now 8.7 million) since 23 hours ago — Italy: +3879 cases (now 4.7 million), +39 deaths (now 131763), +487218 tests (now 100.2 million) since a day ago — Greece: +3541 cases (now 711128), +36 deaths (now 15555), +392407 tests (now 24.3 million) since 23 hours ago | 18:05 |
| Brainstorm | New from ClinicalTrials.gov: (news): Expression of Toll-like Receptors 3 , 7 and 9 in Peripheral Blood Mononuclear Cells of COVID-19 Patients → https://clinicaltrials.gov/ct2/show/NCT05089110 | 18:05 |
| Brainstorm | New from ClinicalTrials.gov: (news): Validation of TERA Bio Station T101 of COVID-19 Tested Population. → https://clinicaltrials.gov/ct2/show/NCT05088902 | 18:16 |
| Brainstorm | New from Contagion Live: Pfizer-BioNTech COVID-19 Vaccine over 90% Effective in Children 5-11: Data presented to the Vaccines and Related Biological Products Advisory Committee (VRBPAC) showed 2 10 µg doses of the Pfizer-BioNTech vaccine to be 90.7% effective in children [... want %more?] → https://www.contagionlive.com/view/pfizer-biontech-covid-19-vaccine-over-90-effective-in-children-5-11 | 18:26 |
| Brainstorm | New from COVID tweets: Josiah Grindrod (@JT_Grindrod): I wish the government reacted to kids getting COVID with the same voracity that they've gone after vaping. → https://twitter.com/JT_Grindrod/status/1451586687847436289 | 18:37 |
| Brainstorm | New from COVID19 Vaccine Tracker: valerie: AnGes: AG0301-COVID19 → https://covid19.trackvaccines.org/vaccines/3/ | 18:48 |
| Brainstorm | New from COVID19 Vaccine Tracker: valerie: Altimmune Inc: AdCOVID → https://covid19.trackvaccines.org/vaccines/75/ | 18:58 |
| Brainstorm | New from COVID19 Vaccine Tracker: valerie: Aivita Biomedical Inc: AV-COVID-19 → https://covid19.trackvaccines.org/vaccines/74/ | 19:10 |
| Brainstorm | New from COVID19 Vaccine Tracker: valerie: AnGes: AG0302-COVID19 → https://covid19.trackvaccines.org/vaccines/31/ | 19:31 |
| Brainstorm | Updates for Dominican Rep.: +1682 cases (now 374722), +5 deaths (now 4100), +9750 tests (now 2.2 million) since 21 hours ago — Luxembourg: +141 cases (now 80603), +5360 tests (now 3.6 million) since 21 hours ago — Canada: +32 deaths (now 28737) since 23 hours ago | 19:32 |
| de-facto | .title https://www.fda.gov/media/153409/download Vaccines and Related Biological Products Advisory Committee October 26, 2021 Meeting Document | 19:50 |
| Brainstorm | de-facto: From www.fda.gov: Vaccines and Related Biological Products Advisory Committee Meeting October 26, 2021 Briefing Document - Sponsor (Pfizer) (Non-FDA) | 19:50 |
| Brainstorm | New from WebMD: COVID Vaccine vs. Flu Vaccine: What to Know: The COVID and flu vaccines are important, and both are quite effective at preventing serious illness or death. But that’s where much of their similarities end. Here’s the science behind both. → https://www.webmd.com/children/vaccines/news/20211022/covid-vaccine-flu-vaccine-what-to-know | 19:52 |
| LjL | i did something stupid though hopelessly consequence free... | 19:55 |
| LjL | i've finally dared enter a couple of stores | 19:55 |
| LjL | second one today, i completely forgot to remove the cotton mask and put on an FFP2 so i went in and stayed for a while with just the cotton mask | 19:56 |
| LjL | you'd figure the way i fret about COVID, i'd be extremely careful about never using anything less than an FFP2 in a store. but my brain sometimes just doesn't operate properly ;( | 19:56 |
| Arsanerit | Are there any statistics how many of unvaccinated people in Germany have recovered from covid in the past six months? | 20:06 |
| de-facto | LjL, hopefully they do some air exchange from time to time also to reduce the risk for their employees as they have to stay in the store the whole day (in contrast to yourself just temporarily spending time there) | 20:06 |
| Arsanerit | there is a total number of recovered but that number likely overlaps with vaccinated people | 20:08 |
| de-facto | what i mean is that the longer you stay the better filter/mask you need for receiving the same contamination dose, yet of course it makes sense to always aim for minimal risk with wearing FFP2 with tight fit when possible | 20:08 |
| Arsanerit | my sister is in both groups | 20:08 |
| LjL | Arsanerit, what are you after, a guess on the chances of recovery if you're unvaccinated? | 20:11 |
| LjL | the "recoveries" most likely don't take into any account whether someone has long COVID, if that's a factor | 20:11 |
| LjL | de-facto, it didn't feel like the HVAC was functioning at all, tbh :( | 20:12 |
| LjL | but maybe i'm wrong | 20:12 |
| de-facto | we somehow have to make sure to get enough air exchange also in the winter, it will be difficult because people will complain about the cold (but fresh) air, maybe we just should wear more layers of clothing or such | 20:15 |
| LjL | so few people use the exposure notification app :( i see it both from my phone's recorded contact graph, and the lethargic numbers at https://www.immuni.italia.it/dashboard.html | 20:15 |
| LjL | de-facto, i took a tram yesterday (for the first time since the pandemic). but i was wearing an Aura and it was a 1928 model tram with openable windows and i basically just stood next to an open window | 20:16 |
| specing | I don't really remember what the app rules were, but weren't you sent to quarantine if you had a high risk contact? | 20:22 |
| de-facto | yeah i also am feeling better with FFP3 in a tram or train | 20:22 |
| specing | or they told you to voluntarily quarantine in that case? | 20:22 |
| specing | And people dont' want to do this, so having such an app is stupid | 20:22 |
| LjL | specing, the contacts i'm talking about are just a statistic of how many other phones with the app installed i've met throughout the day | 20:22 |
| de-facto | specing, afaik the german app is anonymous, hence they dont know if you get a warning by the app or not | 20:23 |
| LjL | you are supposed to quarantine but they cannot enforce it because the app is designed for privacy | 20:23 |
| de-facto | its for estimating the own risk | 20:23 |
| LjL | otherwise people would just not install it | 20:23 |
| LjL | but just look at the numbers i've linked and then compare them with those of the German app | 20:23 |
| LjL | the Italian one has basically been useless | 20:23 |
| de-facto | i mean of course they advise to isolate if the app indicates a risk contact, but ultimately its the decision of the owner of that phone, because there is no possibility for the infrastructure of the app to know if there was a warning or not (its all computed locally, everyone downloads the same list of signatures) | 20:25 |
| Arsanerit | LjL: no | 20:27 |
| Arsanerit | LjL: What I'm after is how many people in total are either vaccinated or recovered; how many people have antibodies. | 20:27 |
| LjL | Arsanerit, okay then there may be studies about that based on random samples of people and seeing if they have antibodies, but random samples are not easy to get | 20:28 |
| LjL | i've definitely seen some studies like that, but 1) don't remember one about Germany and 2) they are often not so reliable | 20:28 |
| Arsanerit | at least in Germany there are also certificates issued based on vaccination or recovery status, because either counts for the covid certificate | 20:28 |
| Arsanerit | so I suspect there may be statistics on how many people have been issued a digital recovery certificate (like sanitary pass in france or green pass in italy) | 20:29 |
| de-facto | yes 6 months immune status after clinically ensured infection status | 20:29 |
| de-facto | Arsanerit, i am not sure if or where, but i would guess RKI would try to do some estimates on that | 20:30 |
| de-facto | (have to admit i am not on the latest state of info regarding Germany right now) | 20:30 |
| leerbi | %cases Switzerland | 20:31 |
| Brainstorm | leerbi: Switzerland has had 862411 confirmed cases (10.0% of all people) and 11193 deaths (1.3% of cases) as of 3 hours ago. 11.5 million tests were done (7.5% positive). 5.7 million were vaccinated (66.2%). +3 cases, +27011 vaccines since 2 hours ago. See https://offloop.net/covid19/?default=Switzerland | 20:31 |
| Brainstorm | leerbi: If you know of an official or otherwise good site for data about Switzerland, with a reasonably short URL, please %tell LjL about it. | 20:31 |
| Brainstorm | Updates for Spain: +2244 cases (now 5.0 million), +43 deaths (now 87151) since 23 hours ago | 20:34 |
| Brainstorm | New from r/WorldNews: worldnews: NIH Admits to Funding Gain-of-Function Research in Wuhan, Says EcoHealth Violated Reporting Requirements → https://old.reddit.com/r/worldnews/comments/qdn580/nih_admits_to_funding_gainoffunction_research_in/ | 20:44 |
| Arsanerit | Is it still true that people who recently recovered can't be vaccinated at all, or was that only when vaccines were scarce? | 20:45 |
| specing | it's not true here | 20:52 |
| Arsanerit | It was true in Germany, but I don't know if it still is. | 20:52 |
| specing | And it wasn't true here in the past | 20:53 |
| de-facto | i dont think that recovered cant be vaccinated in Germany, but there may be a recommended delay time to start with the vaccinations, probably STIKO got some recommendations on that | 20:53 |
| de-facto | it was not recommended back when vaccines were in short supply though | 20:54 |
| de-facto | but that is not the case anymore in Germany (fortunately), because (unfortunately) the demand does not saturate the supply anymore | 20:55 |
| Arsanerit | if demand did saturate the supply that wouldn't last long, because in that case we'd reach near 100% of eligible people within less than two months | 20:56 |
| de-facto | also some people just dont know that they got an (asymptomatic) infection, hence biologically it does not seem to be a problem to get vaccinated in addition to recovery | 20:57 |
| de-facto | in fact their immunity may be among the best then | 20:57 |
| Arsanerit | And since herd immunity with delta and current vaccines is anyway impossible, how important is it for vaccinated people that unvaccinated people get vaccinated? As long as unvaccinated people do not occupy so many hospital beds that regular care is at risk, inhowfar can one still say to get vaccinated is in the /common/ good? | 20:59 |
| Brainstorm | Updates for Maldives: +55 cases (now 86605), +3063 tests (now 1.6 million) since 21 hours ago — Kuwait: +32 cases (now 412481), +1 deaths (now 2460), +14914 tests (now 4.7 million) since 20 hours ago | 20:59 |
| de-facto | yeah but we still did not meet our vaccination goals in Germany and October already shows rising infection numbers again, and a strictly monotonically increasing R~1.2 > 1 means its running out of control further and further when the increase of daily new infections is increasing (R(t) > 1 and dR(t) / dt > 0) | 21:00 |
| de-facto | Arsanerit, its very important because vaccinations are one contribution to a combined (NPIs etc) strategy to significantly reduce R hence come closer to regaining control with R ~ 1 or maintaining control with R < 1 | 21:02 |
| Arsanerit | What will be the peak of the hospitalisation rate and ICU rate if left out of control with current vaccination rates? | 21:02 |
| de-facto | a lot, one probably could model that with differential equations | 21:03 |
| Arsanerit | A lot, but presumably much less than before 85% of 60+ year olds were vaccinated. | 21:04 |
| de-facto | well last winter we did not had Delta | 21:04 |
| de-facto | we have to make the best out of it, but its far from over | 21:04 |
| de-facto | just look at Russia how many problems they have (ok much less vaccinations), but also at UK (where vaccinations alone dont suffice to control it) | 21:05 |
| Arsanerit | What is the situation in the intensive care units in the United Kingdom at present? | 21:06 |
| de-facto | in Germany we are somewhere between those extremes i would assume | 21:06 |
| de-facto | didnt we had like 3M people over 60 years old that did not get vaccinated yet in Germany? | 21:07 |
| de-facto | i guess that could be more than enough to saturate healthcare capacity (that already is getting a constantly increasing load from infections) | 21:07 |
| de-facto | https://www.rki.de/DE/Content/InfAZ/N/Neuartiges_Coronavirus/Situationsberichte/COVID-19-Trends/COVID-19-Trends.html?__blob=publicationFile | 21:09 |
| Arsanerit | depends how many of those 3 million have already had it | 21:09 |
| de-facto | https://www.intensivregister.de/#/aktuelle-lage/zeitreihen | 21:09 |
| de-facto | yes thats true but i doubt that many over 60 years already had a recovery | 21:10 |
| de-facto | hmm R~1.28 >1 at 2021-10-18 according to that RKI dashboard and constantly increasing dR/dt > 0 thats very very bad, it means daily new infections are increasing *faster* than exponentially | 21:13 |
| de-facto | i wish we had something like Italy Green Pass | 21:15 |
| Brainstorm | New from FDA Press Releases: FDA: Coronavirus (COVID-19) Update: October 22, 2021 → http://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-october-22-2021 | 21:15 |
| Arsanerit | I think something like the Italy Green Pass, if necessary even in the workplace, would be highly controversial in Germany. | 21:17 |
| LjL | our green pass isn't anything but the EU certificate | 21:19 |
| LjL | it's called green pass simply because "green certificate" was the original name of the EU project, then they removed the "green" part for some reason, and we shortened certificate into "pass" :P | 21:20 |
| de-facto | but Italy requires employees to decide what strategy they choose to prevent COVID, here in Germany people still can just ignore that necessity imposed on them by the circulating pathogen | 21:21 |
| LjL | even in the US employers are being "kindly asked" to require vaccinations or tests from employees | 21:21 |
| LjL | if the US can mandate things then for sure so can Germany | 21:22 |
| de-facto | one would assume that yes, yet after 2 years still there are no requirements for working places (by private companies) | 21:22 |
| de-facto | well at least not such requirements like the ones by the green pass | 21:23 |
| LjL | %title https://twitter.com/EricTopol/status/1451569056209723395 | 21:25 |
| Brainstorm | LjL: From twitter.com: Eric Topol (@EricTopol): "An assessment of Covid's impact on cognitive function in 740 individuals finds "a relatively high frequency of cognitive impairment several months after patients contracted COVID-19" https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2785388 @JAMANetworkOpen" | 42l - nitter | 21:25 |
| de-facto | LjL, have you seen the paper i linked the other day? | 21:28 |
| de-facto | .title https://www.nature.com/articles/s41593-021-00926-1 | 21:29 |
| Brainstorm | de-facto: From www.nature.com: The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells | Nature Neuroscience | 21:29 |
| de-facto | "Coronavirus disease 2019 (COVID-19) can damage cerebral small vessels and cause neurological symptoms. Here we describe structural changes in cerebral small vessels of patients with COVID-19 and elucidate potential mechanisms underlying the vascular pathology." | 21:29 |
| LjL | "... a range of psychiatric symptoms and may affect up to 76% of patients" *shudder* | 21:30 |
| de-facto | .title https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2785388 | 21:32 |
| Brainstorm | de-facto: From jamanetwork.com: Assessment of Cognitive Function in Patients After COVID-19 Infection | Dementia and Cognitive Impairment | JAMA Network Open | JAMA Network | 21:32 |
| de-facto | "The most prominent deficits were in processing speed (18%, n = 133), executive functioning (16%, n = 118), phonemic fluency (15%, n = 111) and category fluency (20%, n = 148), memory encoding (24%, n = 178), and memory recall (23%, n = 170; Table 2)." | 21:33 |
| de-facto | "In adjusted analyses, hospitalized patients were more likely to have impairments in attention (odds ratio [OR]: 2.8; 95% CI: 1.3-5.9), executive functioning (OR: 1.8; 95% CI: 1.0-3.4), category fluency (OR: 3.0; 95% CI: 1.7-5.2), memory encoding (OR: 2.3; 95% CI: 1.3-4.1), and memory recall (OR: 2.2; 95% CI: 1.3-3.8) than those in the outpatient group." | 21:33 |
| de-facto | "Patients treated in the ED were more likely to have impaired category fluency (OR: 1.8; 95% CI: 1.1-3.1) and memory encoding (OR: 1.7; 95% CI: 1.0-3.0) than those treated in the outpatient setting. No significant differences in impairments in other domains were observed between groups." | 21:33 |
| de-facto | if such things would be long lasting this will significantly influence also the economic performance of a country (apart from load on medical system) | 21:35 |
| de-facto | this is very bad. | 21:35 |
| de-facto | we really need to know how their longterm prognosis most likely will turn out to be | 21:36 |
| LjL | let me quote also for fairness | 21:37 |
| LjL | "The findings of this study are generally consistent with those of research on other viruses (eg, influenza).6 | 21:37 |
| LjL | Limitations of this study include a potential sampling bias, as some participants may have presented to Mount Sinai Health System because of health concerns." | 21:37 |
| de-facto | if its "just" an imbalance by some inflammation that recovery completely or if there is really physical organ damage to the brain (such as shrinking mass by celldeath, or irreversible micro-vessel damage as described above) | 21:37 |
| de-facto | " It is well known that certain populations (eg, older adults) may be particularly susceptible to cognitive impairment after critical illness5; however, in the relatively young cohort in the present study, a substantial proportion exhibited cognitive dysfunction several months after recovering from COVID-19" | 21:38 |
| de-facto | idk man, several months does not sound good to me | 21:38 |
| de-facto | what if there is irreversible brain damage by COVID and a whole nation decides to let it "burn" through their productive population? | 21:39 |
| de-facto | if small vessels just die off and the resources supply does not suffice the demand by those brain cells that were dependent on those vessels before how would they recover from that? | 21:41 |
| de-facto | or if there is ongoing inflammation that is cytotoxic to the brain? | 21:42 |
| de-facto | this may mean that nations with strict ZERO-COVID strategy may take over whole markets if production capacity depends on mental resources (such as IT) | 21:44 |
| Arsanerit | cases in germany are rising fast, but so are cases in italy: http://offloop.net/covid19/?default=United%20Kingdom;France;Italy;Germany;Netherlands;Austria&byPopulation=yes&logScale=yes&cumulative=no&smooth=yes | 21:58 |
| Brainstorm | New from COVID tweets: ChristosArgyropoulos MD, PhD FlozinatorInChief (@ChristosArgyrop): Willing to serve your brain to the virus ? Read this(And note that you can't infer protection by the vaccine against these outcomes : different antibody subclass and location of protection vs severe disease) twitter.com/RolandBakerIII… → https://twitter.com/ChristosArgyrop/status/1451632331526221828 | 21:58 |
| Arsanerit | lower baseline, but slope seems similar | 21:58 |
| Arsanerit | Australia and New Zealand have given up on zero covid, is any country still implementing this successfully? | 21:59 |
| LjL | https://old.reddit.com/r/worldnews/comments/qdo42g/supermarkets_using_cardboard_cutouts_to_hide_gaps/hhns7t7/?context=3 | 22:07 |
| LjL | Dunno what to think. I haven't heard of supply problems in Italy. Well, I guess I have now, but also is there a better way to cause supply issues than to make everyone panic and "stock up"? | 22:07 |
| LjL | Arsanerit: keep in mind Italy started enforcing the green pass for working since Oct 15, and the past couple of days have seen record amount of tests *by far* | 22:11 |
| LjL | Like almost a million in one day instead of the usual 300k | 22:12 |
| LjL | Is you remove the smoothing, it looks more like a sudden jump than a slope | 22:13 |
| MerlinMp[m] | <de-facto> "this may mean that nations..." <- I would rather check if the number of infected is accurate because it makes a difference if 170 of 700 has memory issues or 70.000 undetected infections | 22:15 |
| Arsanerit | LjL: I see, so maybe we see the impact of more testing rather than an actual increase in cases? | 22:15 |
| Arsanerit | let's see what the next 4 weeks bring | 22:15 |
| LjL | Arsanerit: I'm not certain, but the increase in testing is sharp | 22:18 |
| LjL | I haven't looked at ratios of positives to tests lately tbh | 22:19 |
| LjL | I also don't quite understand what that site that was linked to me on Reddit about supposed supply chain issues in Italy is telling me | 22:19 |
| portmanteau | what's zero covid? | 22:19 |
| LjL | There are some orange and red marks but it all seems to be FROM Italy TO other countries | 22:19 |
| portmanteau | Australia and new Zealand gave up on it why? | 22:19 |
| LjL | Maybe I'm missing something from the site because I'm on mobile | 22:20 |
| de-facto | MerlinMp[m], yes of course incidence rates are not directly comparable (nor are cumulative numbers) between nations as the strongly depend on testing | 22:20 |
| LjL | portmanteau: it's a policy of containing covid within a country so that you have virtually zero cases, as opposed to just trying to slow its spread to avoid hospital saturation | 22:21 |
| de-facto | what i meant is what if the real problems with SARS-CoV-2 are actually summarized under the umbrella term that we call long-COVID, what if its not only long but irreversible (to some degree) | 22:21 |
| de-facto | would that actually change the metric that we should employ to estimate the damages imposed by the pathogen? | 22:22 |
| de-facto | portmanteau, with zero-covid i meant that the highest priority is to prevent new infections, hence aim for zero infections of *unknown* origin | 22:23 |
| LjL | I think if we're not fools we're all sort of tacitly taking for granted that these problems will be irreversible to some amount, probably a large amount at this point | 22:23 |
| Arsanerit | how well do vaccinations protect against long covid? | 22:24 |
| LjL | portmanteau: New Zealand has lost control basically | 22:24 |
| LjL | Arsanerit: what I have is a vague 50% | 22:24 |
| de-facto | Arsanerit, irrc vaccine breakthrough cases got half the long-COVID rate | 22:24 |
| LjL | But that's on top of however many symptomatic infections are prevented | 22:24 |
| de-facto | yeah | 22:24 |
| Arsanerit | vaccine breakthrough as in people getting infected despite vaccination or getting sick despite vaccination? | 22:24 |
| portmanteau | sick | 22:25 |
| Arsanerit | okay | 22:25 |
| Arsanerit | better | 22:25 |
| de-facto | hmm good question, afaik long-COVID also can be seen in light cases | 22:25 |
| portmanteau | actually i don't know | 22:25 |
| de-facto | i dont remember the endpoint for that claim exactly anymore, i assume something symptomatic or such | 22:26 |
| de-facto | but it was the same endpoint for both breakthrough and naive infections | 22:26 |
| de-facto | as vaccinated are tested much less often i assume they would need some symptoms to go for a test | 22:27 |
| de-facto | (but thats my speculation now), all i remember clearly is that it was half the rate for long-COVID in breakthrough cases compared with immuno-naive infected | 22:28 |
| Brainstorm | New from CIDRAP: Millions of Americans now eligible for COVID-19 boosters: Stephanie Soucheray | News Reporter | CIDRAP News Oct 22, 2021 In other developments, FDA documents ahead of next week's advisory committee meeting showed the Pfizer vaccine is nearly 91% effective [... want %more?] → https://www.cidrap.umn.edu/news-perspective/2021/10/millions-americans-now-eligible-covid-19-boosters | 22:29 |
| Brainstorm | New from WebMD: Pfizer Vaccine for Kids 90% effective in Preventing COVID-19: As of the first week of October, 16 participants in the placebo group had gotten a symptomatic, lab-confirmed COVID-19 infection compared with just three who caught COVID in the vaccinated group. → https://www.webmd.com/vaccines/covid-19-vaccine/news/20211022/pfizer-vaccine-for-kids-effective | 22:40 |
| de-facto | personally I think its naive to assume the only problem with COVID are the fatal outcomes (or load on healthcare system), imho a MUCH bigger number of "recovered" people get (potentially permanent) problems with their health, apart from the damage to the own body of the individual it also would imply that in addition to the load on healthcare system we would need to take into account the loss of economic production capacity in comparison to | 22:47 |
| de-facto | pre-pandemic performance | 22:47 |
| MerlinMp[m] | <Arsanerit> "better" <- Just for my curiosity - how many people you personally know died of covid or was taken to the hospital? | 22:48 |
| de-facto | to be fair we dont know if their health problems are permanent or if they just having a very slow recovery, but as long as we do *not* know that, imho we should be more careful and not assume "yeah all will be just fine" and let the pathogen rip through our populations | 22:49 |
| de-facto | and long-COVID is a problem that seems to affect also young and fit people (even some athletes etc) that have problems months after their "recovery" (as in not in need for hospital care) | 22:51 |
| de-facto | afaik it also is not strictly required that there were severe COVID symptoms at the time of the ongoing infection in order to suffer from some kind of symptoms many months later, but it may be that more severe COVID cases are overrepresented in some categories of the umbrella term of long-COVID | 22:53 |
| Arsanerit | MerlinMp[m]: died or hospital zero; seriously ill including long covid, several | 22:53 |
| Brainstorm | Updates for India: +15536 cases (now 34.2 million), +666 deaths (now 453742) since 16 hours ago | 23:04 |
| de-facto | .title https://www.medrxiv.org/content/10.1101/2021.10.21.21265133v1 | 23:20 |
| Brainstorm | de-facto: From www.medrxiv.org: Post COVID-19 in children, adolescents, and adults: results of a matched cohort study including more than 150,000 individuals with COVID-19 | medRxiv | 23:20 |
| de-facto | "Utilizing comprehensive healthcare data on more than 45 percent of the German population from January 2019 through December 2020, we investigated post COVID-19 in children/adolescents and adults." | 23:24 |
| de-facto | "The study population included 157,134 individuals (11,950 children/adolescents and 145,184 adults) with confirmed COVID-19. COVID-19 and control cohort were well-balanced regarding covariates." | 23:25 |
| de-facto | "For all health outcomes combined, incidence rates (IRs) in the COVID-19 cohort were significantly higher than those in the control cohort in both children/adolescents (IRR=1.30, 95%-CI=[1.25-1.35], IR COVID-19=436.91, IR Control=335.98) and adults (IRR=1.33, 95%-CI=[1.31-1.34], IR COVID-19=615.82, IR Control=464.15)." | 23:25 |
| de-facto | "IRR estimates were similar for the age groups 0-11 and 12-17. Incidence rates in children/adolescents were consistently lower than those in adults." | 23:26 |
| de-facto | " Among the specific outcomes with the highest IRR and an incidence rate of at least 1/100 person-years in the COVID-19 cohort in children and adolescents were malaise/fatigue/exhaustion (IRR=2.28, 95%-CI=[1.71-3.06], IR COVID-19=12.58, IR Control=5.51), cough (IRR=1.74, 95%-CI=[1.48-2.04], IR COVID-19=36.56, IR Control=21.06), and throat/chest pain (IRR=1.72, 95%-CI=[1.39-2.12], IR COVID-19=20.01, IR Control=11.66)." | 23:27 |
| de-facto | "In adults, these included dysgeusia (IRR=6.69, 95%-CI=[5.88-7.60], IR COVID-19=12.42, IR Control=1.86), fever (IRR=3.33, 95%-CI=[3.01-3.68], IR COVID-19=11.53, IR Control=3.46), and dyspnea (IRR=2.88, 95%-CI=[2.74-3.02], IR COVID-19=43.91, IR Control=15.27)." | 23:30 |
| de-facto | "This large, matched cohort study indicates substantial new-onset post COVID-19 morbidity in pediatric and adult populations based on routine health care documentation. Further investigation is required to assess the persistence and long-term health impact of post COVID-19 conditions, especially in children and adolescents. | 23:30 |
| de-facto | " | 23:30 |
| Brainstorm | New from COVID tweets: Alexis Villani (@VillaniAlexis): Had a wonderful time talking to @VirusesImmunity at the IgE equity Symposium. I’m lucky to have had the opportunity to talk to such an inspiration of mine! Though an in-person convo is deeply missed! Ah COVID. → https://twitter.com/VillaniAlexis/status/1451661121572667392 | 23:32 |
| de-facto | .title https://www.medrxiv.org/content/10.1101/2021.10.18.21265168v1 | 23:33 |
| Brainstorm | de-facto: From www.medrxiv.org: Who has long-COVID? A big data approach | medRxiv | 23:33 |
| de-facto | "Using the National COVID Cohort Collaborative (N3C) EHR repository, we developed XGBoost machine learning (ML) models to identify potential long-COVID patients." | 23:33 |
| de-facto | "We examined demographics, healthcare utilization, diagnoses, and medications for 97,995 adult COVID-19 patients. We used these features and 597 long-COVID clinic patients to train three ML models to identify potential long-COVID patients among (1) all COVID-19 patients, (2) patients hospitalized with COVID-19, and (3) patients who had COVID-19 but were not hospitalized." | 23:34 |
| de-facto | "Our models identified potential long-COVID patients with high accuracy, achieving areas under the receiver operator characteristic curve of 0.91 (all patients), 0.90 (hospitalized); and 0.85 (non-hospitalized)." | 23:34 |
| -RSSBot[LjLmatrix- Zotero / COVID links Group / Top-Level Items: Post COVID-19 in children, adolescents, and adults: results of a matched cohort study including more than 150,000 individuals with COVID-19 ( https://www.zotero.org/groups/covid_links/items/AFJFN5FH ) | 23:36 | |
| de-facto | thats pretty cool if they can identify long covid patients with such accuracy, it may help with monitoring changes in attack rates for long-COVID | 23:40 |
| Dredd | My 12 year old brother had his vaccine the other week | 23:50 |
| Dredd | Spoke to him about it yesterday and he said "it contains snake venom so I regret having it" | 23:50 |
| Dredd | Which then turned to "it has bad things that I don't want in my blood" | 23:50 |
| Dredd | Then it turned out "I saw this on the internet somewhere" | 23:51 |
| Brainstorm | New from COVID tweets: Brian Hjelle, virologist (@hjelle_brian): Even COVID virus says it doesn't have violins small enough for those fired for refusing vax. pic.twitter.com/EFWXivU0zQ → https://twitter.com/hjelle_brian/status/1451665835710316545 | 23:53 |
| de-facto | hmm maybe try to help him estimate the quality of information sources (in the world wide web) and also that relying on a single source is problematic | 23:53 |
| de-facto | this is a very important skill, i thought the younger generations get trained for pinpointing BS much easier with all those contradicting memes circulating in the social networks | 23:54 |
| Arsanerit | In secondary school around 2000 we had training in having a skeptical approach to information on the world wide web | 23:55 |
| Arsanerit | I remember doing a project analysing the claims made on a website about "transcendental meditation". | 23:55 |
| Arsanerit | One of the most important skills I learned in secondary school. | 23:55 |
| de-facto | yes its extremely important | 23:56 |
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