libera/##covid-19/ Wednesday, 2023-01-18

BrainstormNew from The Lancet (Online): [Articles] Pregnancy outcomes and vaccine effectiveness during the period of omicron as the variant of concern, INTERCOVID-2022: a multinational, observational study: COVID-19 in pregnancy, during the first 6 months of omicron as the variant of concern, was [... want %more?] → https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)02467-9/fulltext00:33
-Bridgestorm- ⭕ Gempa bumi! Lindu! Earthquake! 6.4 M tremor, registered by infoBMKG, occurred 3 minutes ago (00:34:46 UTC), during daytime, Bilungala, Indonesia (-0.07, 123.28), ↓138 km likely felt 350 km away (in Gorontalo…) by 150000 people → https://twitter.com/infoBMKG/status/1615508812420755456 (Twitter)01:38
BrainstormUpdates for Slovakia: +157 cases since 15 hours ago02:06
BrainstormNew from r/COVID19: COVID19: Therapeutic and vaccine-induced cross-reactive antibodies with effector function against emerging Omicron variants → https://old.reddit.com/r/COVID19/comments/10etlwi/therapeutic_and_vaccineinduced_crossreactive/02:10
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Important new report from @veeslerlab comparing bivalent booster vs Wu/original, documenting advantage of the bivalentbiorxiv.org/content/10.110…2 key points from an outstanding summary thread on enhanced memory B cell response, cross-immunity to other variants [... want %more?] → https://twitter.com/EricTopol/status/161553450702066892803:29
BrainstormNew from ##covid-19 Zotero group: Therapeutic and vaccine-induced cross-reactive antibodies with effector function against emerging Omicron variants: Type Preprint Author Amin Addetia Author Luca Piccoli Author James Brett Case Author Young-Jun Park Author Martina Beltramello Author Barbara Guarino Author Ha Dang [... want %more?] → https://www.zotero.org/groups/covid_links/items/W35GF4Q903:48
LjLi'm not clear whether this is "yay" or "boo" news03:51
LjLbut i like it how "imprinting" is now being used as the word for "original antigenic sin" because that one has already been "burned" by saying it wouldn't happen... :P03:52
BrainstormNew from ##covid-19 Zotero group: LjL: Important new report from @veeslerlab comparing bivalent booster vs Wu/original, documenting advantage of the bivalent https://biorxiv.org/content/10.1101/2023.01.17.523798v1 2 key points from an outstanding summary thread on enhanced memory B cell response, cross-immunity to [... want %more?] → https://www.zotero.org/groups/covid_links/items/BX35QR9403:58
BrainstormUpdates for Trinidad and Tobago: +519 cases, +12 deaths since 6 days ago — Mauritania: +229 cases since 6 days ago — Jamaica: +175 cases, +11 deaths since 6 days ago — Malawi: +164 cases since a day ago04:04
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The heart and #LongCovid: a systematic review and meta-analysis of over 100 studies, with 16 meeting high-quality criteria, finds ~10% people infected had enduring symptoms (several months to >1 year) of chest pain and arrhythmiasmedrxiv.org/content/10.110… [... want %more?] → https://twitter.com/EricTopol/status/161554346206942822404:07
BrainstormNew from ##covid-19 Zotero group: Long-term cardiac symptoms following COVID-19: a systematic review and meta-analysis: Type Preprint Author Boya Guo Author Chenya Zhao Author Mike Z. He Author Camilla Senter Author Zhenwei Zhou Author Jin Peng Author Song Li Author Annette L. Fitzpatrick Author Sara Lindstroem [... want %more?] → https://www.zotero.org/groups/covid_links/items/NMDSJ6M304:17
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): A new @ShanLuLiu1 @OhioState lab study shows superiority of bivalent booster compared with original booster against XBB.1.5, CH.1.1 and other variantsbiorxiv.org/cgi/content/sh… along with higher XBB.1.5 infectivity pic.twitter.com/IR8rSNX3CY → https://twitter.com/EricTopol/status/161555365394294784004:46
BrainstormUpdates for Germany: +15450 cases, +188 deaths since 23 hours ago — Pakistan: +24 cases since a day ago05:06
BrainstormUpdates for Illinois, United States: +16602 cases, +136 deaths since 12 days ago — New York, United States: +10254 cases, +62 deaths since a day ago — New Jersey, United States: +6963 cases, +14 deaths since 4 days ago — Kyoto, Japan: +2891 cases, +10 deaths since a day ago07:05
BrainstormNew from r/COVID19: COVID19: Extraordinary Evasion of Neutralizing Antibody Response by Omicron XBB.1.5, CH.1.1 and CA.3.1 Variants → https://old.reddit.com/r/COVID19/comments/10f16sm/extraordinary_evasion_of_neutralizing_antibody/08:26
BrainstormNew from r/COVID19: COVID19: Redistribution and activation of CD16bright CD56dim NK cell subset to fight against Omicron subvariant BA.2 after COVID-19 vaccination → https://old.reddit.com/r/COVID19/comments/10f1ovr/redistribution_and_activation_of_cd16bright/08:55
BrainstormUpdates for Taiwan: +21021 cases, +26 deaths, +27104 tests since 23 hours ago09:03
BrainstormNew from r/Coronavirus: Daily Discussion Thread | January 18, 2023: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/10f1sxc/daily_discussion_thread_january_18_2023/09:05
BrainstormNew from COVID on Twitter: (translated) Marc Veldhoen (@Marc_Veld): This is not in the heart and not in blood vessels. This is again false information to create confusion. Vaccines actually ensure that a virus is cleared up more quickly with much less damage.Don't fall for it; these are charlatans. pic.twitter.com/Eb2njpHhLm → https://twitter.com/Marc_Veld/status/161562295490941747209:14
BrainstormUpdates for Maharashtra, India: +33 cases, +1 deaths since 23 hours ago — Delhi, India: +11 cases since 2 days ago — Gujarat, India: +6 cases since 4 days ago — Haryana, India: +3 cases since 23 hours ago09:59
BrainstormUpdates for Russia: +5478 cases, +46 deaths since 23 hours ago11:01
-Bridgestorm- 🏠 Deprem! Earthquake! 5.9 Ml tremor, registered by 5 agencies, with 30 reports, occurred 10 minutes ago (10:08:12 UTC), during daytime, Khowy, Iran, Islamic Republic of (38.49, 44.8), ↓2 km likely felt 290 km away (in خوی…) by 469300 people (www.seismicportal.eu)11:18
BrainstormNew from r/Science: science: New Research Shows Pandemic’s Toll on Frontline Health Care Workers → https://old.reddit.com/r/science/comments/10f2hul/new_research_shows_pandemics_toll_on_frontline/11:21
BrainstormNew from Reddit (test): nCoV: Global COVID Cases For 18JAN22 → https://old.reddit.com/r/nCoV/comments/10f43qm/global_covid_cases_for_18jan22/11:31
BrainstormNew from r/COVID19: Random symptoms: Hey all, so I tested positive for the first time on Saturday. I've had a wave of issues... Dizziness, headache, sinus pain, lost smell and taste, teeth and jaw aching along with all other muscles.. Today I Have a sore in my mouth! From what I gather this is the parotid [... want %more?] → https://old.reddit.com/r/COVID19/comments/10f4ceh/random_symptoms/11:51
BrainstormUpdates for Israel: +1190 cases, +8 deaths since a day ago12:03
BrainstormNew from PubMed: Functionalized Fullerene for Inhibition of SARS-CoV-2 Variants: As virus outbreaks continue to pose a challenge, a nonspecific viral inhibitor can provide significant benefits, especially against respiratory viruses. Polyglycerol sulfates recently emerge as promising agents that mediate interactions between cells [... want %more?] → https://pubmed.ncbi.nlm.nih.gov/36651127/13:07
BrainstormNew from BMJ: The BMJ Appeal 2022-23: How safe burial helped end the 2022 Ebola epidemic: The latest outbreak of Ebola virus disease, reported in nine districts of Uganda in September 2022,1 was declared officially over by the country’s Ministry of Health on 11 January. A total of 142 cases and 55 deaths have been reported, [... want %more?] → http://www.bmj.com/content/380/bmj.p92.short13:17
BrainstormNew from Novavax: (news): Novavax Nuvaxovid COVID-19 Vaccine Approved in South Korea as an Adult Booster → https://ir.novavax.com/2023-01-18-Novavax-Nuvaxovid-COVID-19-Vaccine-Approved-in-South-Korea-as-an-Adult-Booster14:06
BrainstormUpdates for Nepal: +9 cases since 23 hours ago14:08
BrainstormNew from Johnson&Johnson: Janssen and Global Partners to Discontinue Phase 3 Mosaico HIV Vaccine Clinical Trial: Independent, scheduled review of Phase 3 Mosaico study finds investigational vaccine regimen lacks efficacy in preventing HIVNo vaccine-related safety [... want %more?] → https://www.jnj.com/janssen-and-global-partners-to-discontinue-phase-3-mosaico-hiv-vaccine-clinical-trial14:36
BrainstormNew from COVID on Twitter: Bloom Lab (@jbloom_lab): Contrast below Tweet w one in tweet 22 of same thread by @veeslerlabXBB.1 only has ~4-fold decrease in antibody *binding* to RBD but ~100+ fold decrease in *neutralization*Underscores how SARS-CoV-2 preferentially evolving to escape antibody neutralization [... want %more?] → https://twitter.com/jbloom_lab/status/161570813252065689614:55
BrainstormUpdates for Kosovo: +17 cases since a day ago15:04
BrainstormNew from StatNews: Pharma: STAT+: Pharmalittle: HIV vaccine study is stopped early; Merck has a plan to combat carcinogen found in diabetes drugs → https://www.statnews.com/pharmalot/2023/01/18/hiv-vaccines-carcinogen-merck-pfizer-patents-rsv-moderna-jnj-obesity-wegovy-pathogens-fda-abortion-mifepristone/15:25
BrainstormUpdates for Austria: +2643 cases, +13 deaths since 23 hours ago — Azerbaijan: +75 cases, +6 deaths since a day ago — Saudi Arabia: +35 cases, +3 deaths, +4220 tests since a day ago16:06
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): There are now 10 lab studies that compared the bivalent BA.5 with the original booster. Overall they demonstrate improved neutralizing antibodies to not only BA.5, but also XBB and other new variants I've updated the summary of the lab and clinical data [... want %more?] → https://twitter.com/EricTopol/status/161572847386322944116:13
LjL-MatrixNew from r/Coronavirus: Coronavirus: DeSantis proposes policy permanently banning Covid-19 vaccine and mask requirements and other pandemic mitigation measures in Florida | CNN Politics → https://old.reddit.com/r/Coronavirus/comments/10f9bhb/desantis_proposes_policy_permanently_banning/17:02
* LjL-Matrix rolls eyes17:02
BrainstormNew from ClinicalTrials.gov: (news): COVID-19 Vaccines and the Menstrual Cycle → https://clinicaltrials.gov/ct2/show/NCT0568899517:03
BrainstormNew from ClinicalTrials.gov: (news): A Study of Jacktinib Hydrochloride Tablets in the Treatment of Severe Novel Coronavirus Pneumonia → https://clinicaltrials.gov/ct2/show/NCT0568883917:23
BrainstormNew from ClinicalTrials.gov: (news): Evusheld Japan PMS_Japan Post-Marketing Surveillance (PMS) → https://clinicaltrials.gov/ct2/show/NCT0568787717:33
BrainstormNew from ClinicalTrials.gov: (news): UC-MSCs in the Treatment of Severe and Critical COVID-19 Patients With Refractory Hypoxia → https://clinicaltrials.gov/ct2/show/NCT0568900817:43
BrainstormNew from ClinicalTrials.gov: (news): Multicenter Randomized Double-blind Placebo-controlled Study to Investigate Azvudine in Symptomatic Adults With COVID-19 at Increased Risk of Progressing to Severe Illness → https://clinicaltrials.gov/ct2/show/NCT0568903417:52
BrainstormUpdates for Myanmar: +14 cases since a day ago18:11
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The benefit of vaccination after Covid to prevent #LongCovid, a ~40% reduction, across multiple organ systems (including lung, neurologic, diabetes)jamanetwork.com/journals/jaman… @JAMANetworkOpen pic.twitter.com/d1HuxaLDKm → https://twitter.com/EricTopol/status/161575708679695155318:13
BrainstormNew from WebMD: Can ‘Radical Rest’ Help With Long COVID Symptoms?: There’s growing evidence that overexertion and not getting enough rest in that acute phase of COVID-19 infection can worsen longer-term symptoms. → https://www.webmd.com/covid/news/20230118/can-radical-rest-help-long-covid-symptoms18:52
BrainstormUpdates for Chile: +3019 cases, +9 deaths, +16904 tests since a day ago19:01
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The pervasive denialism of #LongCovid is sickening. And blaming it on vaccines, which help to provide protection against it, is absolutely pathetic. twitter.com/BlairCraig16/s… → https://twitter.com/EricTopol/status/161578215431066828819:50
BrainstormUpdates for Malaysia: +371 cases, +4 deaths since a day ago20:03
BrainstormNew from r/COVID19: COVID19: Differences Between Reported COVID-19 Deaths and Estimated Excess Deaths in Counties Across the United States, March 2020 to February 2022 → https://old.reddit.com/r/COVID19/comments/10ffblf/differences_between_reported_covid19_deaths_and/20:09
BrainstormUpdates for Canada: +4 deaths since 22 hours ago21:05
BrainstormUpdates for South Africa: +874 cases since a day ago — Lebanon: +269 cases, +3 deaths since 23 hours ago22:07
BrainstormNew from r/COVID19: COVID19: COVID-19 Induces Senescence and Exhaustion of T Cells in Patients with Mild/Moderate and Severe Disease during a Seven-Day Interval → https://old.reddit.com/r/COVID19/comments/10fi098/covid19_induces_senescence_and_exhaustion_of_t/22:17
LjLthat sounds scary22:20
LjLdon't T cells basically not regenerate (almost)?22:20
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Over 10 years (greatly exceeding the mouse lifespan) and 51 successive immunizations, T cells remained competent to respond to vaccination!!Cells required sufficient rest between stimulation events. pic.twitter.com/l3xYNMFmaG → https://twitter.com/Marc_Veld/status/161581991699247104022:27
canogrnbeanswhat's up?22:31
BrainstormUpdates for Canada: +628 cases since 2 hours ago23:10
BrainstormNew from Contagion Live: us: Investigational Janssen HIV Vaccine Found to be Ineffective, Study Discontinued → https://www.contagionlive.com/view/investigational-janssen-hiv-vaccine-found-to-be-ineffective-study-discontinued23:15
BrainstormNew from r/Coronavirus: Coronavirus: NYC records 400 COVID deaths in 2 weeks as PCR testing drops → https://old.reddit.com/r/Coronavirus/comments/10fjvte/nyc_records_400_covid_deaths_in_2_weeks_as_pcr/23:44

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