libera/##covid-19/ Thursday, 2023-02-09

BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Consistent across pre-specified subgroups, notably vaccinated (84%) and the unvaccinated pic.twitter.com/Bovuyn71hq → https://twitter.com/EricTopol/status/162345563475371622500:05
BrainstormUpdates for Lebanon: +216 cases, +3 deaths since 2 days ago00:05
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Severe COVID-19 patients have impaired plasmacytoid dendritic cell-mediated control of SARS-CoV-2IFN production is critical to control SARS-CoV-2: its main producers pDC are also critical.nature.com/articles/s4146… → https://twitter.com/Marc_Veld/status/162346046584937676900:25
BrainstormNew from Contagion Live: No New COVID-19 Variants Coming From China in Latest Wave: Chinese investigators said genome analysis suggests 2 existing Omicron sub-variants, BA52 and BF7, were among the most dominant variants in Beijing. → https://www.onclive.com/view/no-new-covid-19-variants-coming-from-china-in-latest-wave00:35
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): New @bmj_latestProtection for newborns/infants by maternal vaccinationbmj.com/content/380/bm… pic.twitter.com/puT8gu1KwS → https://twitter.com/EricTopol/status/162346905178277888000:54
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Why are doctors so polarized about Covid treatments (HCQ, ivermectin, vaccines)? pnas.org/doi/10.1073/pn…"The preference for @FoxNews is a significant predictor of 8 outcomes (controlling for political ideology)""Political ideology colors the evaluation of [... want %more?] → https://twitter.com/EricTopol/status/162347230913800192101:13
BrainstormUpdates for Canada: +1155 cases, +24 deaths since 6 hours ago02:10
BrainstormUpdates for Norway: +60 cases since 23 hours ago — Ivory Coast: +12 cases, +242 tests since 23 hours ago03:00
BrainstormNew from r/Science: science: A single injection of a new COVID-19 antiviral treatment cut the risk of hospitalization for infection in half in clinical trials → https://old.reddit.com/r/science/comments/10xh1ap/a_single_injection_of_a_new_covid19_antiviral/03:09
BrainstormNew from COVID on Twitter: BNO News (@BNOFeed): U.S. COVID update:- New cases: 108,067- Average: 40,244 (-814)- States reporting: 29/50- In hospital: 29,392 (+1,004)- In ICU: 3,718 (+16)- New deaths: 1,111- Average: 551 (+1) → https://twitter.com/BNOFeed/status/162351111058539315203:48
LjLhttps://www.nejm.org/doi/full/10.1056/NEJMoa2209760 ← (the above from r/science) credible?04:05
LjLi'm not sure any treatment would get much use given Paxlovid doesn't, but, i'd still like to have treatments available...04:06
LjLCOVID is "over" in all sorts of ways according to people, but then even as children are arguably least impacted, I read it's a leading cause of death among them. I mean, sure, they don't die a lot in developed countries, but... do we positively want them to? O.o04:07
LjLI hear "think of the children" so many times about things that have very little to do with them, but when it's time to actually protect their lives, "meh"04:07
BrainstormUpdates for Pakistan: +17 cases since 23 hours ago05:04
BrainstormUpdates for Tennessee, United States: +10249 cases, +79 deaths since 6 days ago — Germany: +18011 cases, +127 deaths since a day ago06:00
BrainstormUpdates for Pennsylvania, United States: +11154 cases, +130 deaths since 7 days ago — North Rhine-Westphalia, Germany: +5910 cases, +29 deaths since 23 hours ago — Moscow, Russia: +3116 cases, +12 deaths since 23 hours ago — Kansas, United States: +1945 cases, +26 deaths since a day ago07:03
BrainstormNew from r/Coronavirus: Daily Discussion Thread | February 09, 2023: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/10xp5yh/daily_discussion_thread_february_09_2023/09:05
BrainstormUpdates for UAE: +127 cases since 21 hours ago09:08
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Fluenz Tetra, influenza vaccine (live attenuated, nasal), Influenza, Human, Date of authorisation: 04/12/2013, Revision: 23, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/fluenz-tetra09:24
BrainstormNew from BioNTech: Statement on Humanitarian Aid in Türkiye, Syria and Ukraine: Prof. Ugur Sahin, CEO and Co-Founder of BioNTech: “We at BioNTech are saddened by the tragic loss of many lives as a result of the earthquakes that hit Türkiye and Syria. At [... want %more?] → https://investors.biontech.de/news-releases/news-release-details/statement-humanitarian-aid-turkiye-syria-and-ukraine09:34
BrainstormUpdates for Uttar Pradesh, India: +5 cases, +1 deaths since 23 hours ago10:04
BrainstormNew from BBC Health: Cervical cancer: Health trusts miss abnormal cells in smear tests: A 45-year-old woman says she was devastated after learning that three previous checks had been misread. → https://www.bbc.co.uk/news/uk-northern-ireland-6437396410:22
BrainstormNew from StatNews: What people on Medicare can expect once the Covid-19 public health emergency ends: Medicare enrollees will pay more for Covid tests after the public health emergency ends, according to the agency that oversees the program. → https://www.statnews.com/2023/02/09/medicare-covid-tests-emergency-ends/10:52
BrainstormNew from PubMed: Tumour-derived small extracellular vesicles contribute to the tumour progression through reshaping the systemic immune macroenvironment: CONCLUSIONS: These results highlight that tumour-derived sEVs function as a bridge between peripheral immunity regulation and the tumour microenvironment, and contribute to cancer [... want %more?] → https://pubmed.ncbi.nlm.nih.gov/36755063/11:02
BrainstormNew from BBC Health: NHS Tracker: Find out about hospital waiting times in your area this winter: Flu, staff shortages and Covid backlogs are putting the NHS under severe strain, find out what's happening in your area. → https://www.bbc.co.uk/news/health-5954980012:10
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): We Still Don’t Know What Works Best to Slow the Spread Of COVID-19Which government measures had the greatest and the least impact? How did the sequencing and timing of these NPIs affect their effectiveness? Which measures caused more harm than benefit? [... want %more?] → https://twitter.com/Marc_Veld/status/162364091623694336312:20
BrainstormNew from Reddit (test): nCoV: Global COVID Cases For 09FEB23 → https://old.reddit.com/r/nCoV/comments/10xsv6n/global_covid_cases_for_09feb23/13:00
ublx%title https://www.nature.com/articles/d41586-023-00347-z14:05
Brainstormublx: From www.nature.com: COVID drug drives viral mutations — and now some want to halt its use14:05
ublxnature.com note on January 27th medrxiv preprint: https://www.medrxiv.org/content/10.1101/2023.01.26.23284998v214:06
ublx%title14:06
Brainstormublx: From www.medrxiv.org: Identification of a molnupiravir-associated mutational signature in SARS-CoV-2 sequencing databases | medRxiv14:06
BrainstormNew from r/COVID19: COVID19: Potential antiviral effects of pantethine against SARS-CoV-2 → https://old.reddit.com/r/COVID19/comments/10xtjtz/potential_antiviral_effects_of_pantethine_against/14:07
BrainstormUpdates for Russia: +12301 cases, +41 deaths since a day ago14:07
BrainstormNew from BBC Health: Cervical cancer: Health trusts miss abnormal cells in smear tests: A 45-year-old woman says she was devastated after learning that three previous checks had been misread. → https://www.bbc.co.uk/news/uk-northern-ireland-6437396414:27
BrainstormNew from StatNews: Pharma: STAT+: Pharmalittle: Study of Covid-19 therapy revives debate over FDA clearance; pharma companies are ready to make deals → https://www.statnews.com/pharmalot/2023/02/09/covid19-dealmaking-lilly-centene-discrimination-teva-antitrust-bayer-astrazeneca/15:25
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Spikevax (previously COVID-19 Vaccine Moderna), elasomeran,imelasomeran and elasomeran,davesomeran and elasomeran,COVID-19 mRNA vaccine (nucleoside-modified), COVID-19 virus infection, Date of [... want %more?] → https://www.ema.europa.eu/en/medicines/human/EPAR/spikevax16:04
BrainstormNew from COVID on Twitter: Dakota (@Dakota_150): Osterholm Update: "Episode 124: Taking Long COVID Seriously"open.spotify.com/episode/6geznP… → https://twitter.com/Dakota_150/status/162370524909654016017:04
BrainstormNew from Il Sole 24 Ore: (translated) “Who will cure us. Notes on the future of public health»: Il Sole 24 Ore offers on newsstands for a month from Saturday 11 February and in bookshops from 3 March the volume by Paolo Nucci, full professor of Ophthalmology at the University of Milan, [... want %more?] → https://www.ilsole24ore.com/art/chi-ci-curera-appunti-futuro-sanita-pubblica-AER1OYkC17:24
BrainstormNew from COVID on Twitter: Dr Emma Hodcroft (@firefoxx66): By the way... I'll be at #CROI #CROI2023 in 2 weeks, in #Seattle! If you're around, I'd be very happy to meet!Also, I'll be speaking in a fantastic #HIV/#SARSCoV2 session with @MichaelWorobey & @PaulBieniasz on Monday afternoon - come join the discussion! [... want %more?] → https://twitter.com/firefoxx66/status/162372208266720051417:43
BrainstormNew from COVID on Twitter: Nextstrain (@nextstrain): Based on its rapid growth in multiple geographies, we've designated the recombinant @PangoNetwork lineage XBB.1.5 & its descendants as clade 23A, labelled "23A (Omicron)" on Nextstrain trees.23A (XBB.1.5) is a descendant of the recombinant 22F (XBB).1/7 [... want %more?] → https://twitter.com/nextstrain/status/162372398770756403417:53
BrainstormNew from COVID on Twitter: Theo Sanderson (@theosanderson): For avoidance of doubtIn our preprint we identify a signature of molnupiravir: associated branches have very few (<10%) transversion mutations. Omicron (B.1.1.529) defining mutations are 43% transversions -- i.e. this variant did not emerge from [... want %more?] → https://twitter.com/theosanderson/status/162372834151670989118:03
BrainstormUpdates for Chile: +1823 cases, +22 deaths since a day ago18:10
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): An inhaled hydrogel shield coats the airway to prevent Covid infections, yet another way to get ahead of  this virus, no less other respiratory pathogensnature.com/articles/s4156… @NatureMaterials pic.twitter.com/E9q8ZsYf8t → https://twitter.com/EricTopol/status/162372927396527308818:12
BrainstormNew from ##covid-19 Zotero group: (translated) Early Treatment with Pegylated Interferon Lambda for Covid-19: Type Journal Article Author Gilmar Reis Author Eduardo A.S. Moreira Silva Author Daniela C. Medeiros Silva Author Lehana Thabane Author Vitoria H.S. Campos Author Thiago S. Ferreira Author Castilho V.Q. [... want %more?] → https://www.zotero.org/groups/covid_links/items/VS9QVCAA18:22
BrainstormNew from ##covid-19 Zotero group: Why the Odds Are Stacked Against a Promising New Covid Drug: Type Newspaper Article Author Benjamin Mueller URL https://www.nytimes.com/2023/02/08/health/covid-drug-eiger-interferon.html Publication The New York Times ISSN 0362-4331 Date 2023-02-08 Section Health Accessed 2023-02-09 [... want %more?] → https://www.zotero.org/groups/covid_links/items/9VY7NNPJ18:32
BrainstormNew from COVID on Twitter: Florian Krammer (@florian_krammer): 3) ...is now the seasonal H1N1 strain and features and avian origin N1 (see 1968 H2N2/H3N2 cross-protection for literature). Then, physicians need to be informed about the possibility that an atypical influenza they detect is H5N1. They need to [... want %more?] → https://twitter.com/florian_krammer/status/162374280063759564819:01
BrainstormNew from COVID on Twitter: Florian Krammer (@florian_krammer): 4)...and what these tests can pick up. Furthermore, the public needs to be informed not to touch any dead or weirdly behaving birds or mammals. But it should be clear in general. Finally, we probably want to have a discussion about vaccination of [... want %more?] → https://twitter.com/florian_krammer/status/162374333556657356819:11
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): XBB.1.5 quickly rising to dominance in Austria & clearly behind the recent uptick in cases... This is the first recombinant lineage now that will become dominant... Luckily, the infection fatality rate & infection hospitalisation rate have come down [... want %more?] → https://twitter.com/TWenseleers/status/162374997167254732819:30
BrainstormUpdates for Malaysia: +269 cases since a day ago — United Kingdom: +446 deaths since 6 days ago — Canada: +29 deaths since 21 hours ago20:09
BrainstormNew from StatNews: Listen: The return of bird flu and the effects of pandemic fatigue: Just how alarming is bird flu? And did we learn enough from Covid-19 to be sensible about it? All that and more on the new episode of "The Readout LOUD"… → https://www.statnews.com/2023/02/09/podcast-bird-flu-h5n1-pandemic-fatigue/20:38
BrainstormUpdates for Ukraine: +3708 cases, +68 deaths since 9 hours ago21:11
BrainstormUpdates for Jamaica: +276 cases, +4 deaths since 7 days ago22:01
BrainstormNew from Contagion Live: No Increased Risk of Serious Adverse Events After COVID-19 Vaccination: After an 18-month study, investigators determined none of the diseases examined were more frequent among the vaccinated than among the non-vaccinated. → https://www.onclive.com/view/no-increased-risk-of-serious-adverse-events-after-covid-19-vaccination22:06
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Who gets better COVID protection? CEOs or the frontline workers they employ? "With the dangers of delayed heart disease, memory and disorders cognition, along with post-COVID immune dysfunction, we are dealing with a [... want %more?] → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/10y6eft/who_gets_better_covid_protection_ceos_or_the/22:15
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Immunodysfunction: A Cause of Stealth COVID-19 Illness and Death → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/10y6hep/immunodysfunction_a_cause_of_stealth_covid19/22:25
BrainstormUpdates for Azerbaijan: +37 cases since a day ago23:09

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