libera/##covid-19/ Friday, 2023-04-07

BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): This also relates to the very interesting report of #SARSCoV2 spike protein found in the skull-meninges-brain axis todaytwitter.com/EricTopol/stat… → https://twitter.com/EricTopol/status/164409985373847142600:11
dmb_talked to doc today, they said ER would laugh you out after waiting 3 hours if I went it for a fever of 103 at my age00:28
ublixdmb_: which country is this in?00:33
dmb_US00:33
ublixwhat did the doctor say was a temperature that does merit medical attention?00:34
dmb_ER hospitals are known to be very very slow here00:34
dmb_he said 105-10600:34
dmb_to get urgent help if so00:34
ublixso00:35
ublix103 = bust out laughing00:35
ublix105 = get urgent help00:35
dmb_basically00:35
ublixseems legit00:35
dmb_he didn't say laugh you out technically, but said they will tell you to go home eventually00:36
ublixwonder if this view was in the context of covid where fever is expected00:36
ublixie i wonder what view would be taken of 103+ fever with no apparent cause00:37
dmb_yeah, could be true, 103+ without cause might raise some flags00:37
dmb_but could also be flu i guess?00:37
ublixi only had a high fever once, when i was about 10 or so. not that i can remember it, but a doctor was called00:39
ublixbut what does that actually feel like?00:40
dmb_headaches, cold, achy00:40
ublixi mean, 103 and beyond, is your thinking degraded?00:40
dmb_maybe a little dizzy00:40
dmb_i can't stand up for long00:40
ublixand that's at 103?00:41
dmb_and once that fever breaks though, you feel so warm, my cheeks were red and sweat00:41
dmb_for me at least, mainly feel cold and want to bundle more00:41
dmb_which of course isn't that good00:41
ublixpresumably things deteriorate in a non-linear fashion as you go past 104,10500:41
ublixi mean, if you live alone, will you be able to "get urgent medical help" if you're at 105?00:42
dmb_i guess its a 911 call at that point if you are alone00:42
dmb_i don't know00:42
dmb_doctor seemed pretty confident I am fine00:42
ublixyou're fever is receding?00:44
dmb_i told him it was 102, he said that is fine00:44
dmb_its up and down00:44
dmb_probably from tylenol00:44
dmb_tylenol = acetaminophen here00:45
ublix= paracetamol here in UK00:46
ublixyou ever do anything like cold water soaked face cloth on your forehead?00:47
dmb_thats a hard name to market it seems00:47
dmb_actually yeah, not because it helps, but because it feels good00:47
ublixhmm00:47
dmb_cools me down when fever breaks00:47
dmb_was tempted to do a coolish shower also00:47
ublixspose you want to time the last allowable acetaminophen dose for the day for best effect right before sleep00:49
dmb_yeah, thats a pain actually00:50
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): How Covid is transmitted in households, via a prospective study and dense longitudinal testing (through Alpha variant wave)thelancet.com/journals/lanmi… @LancetMicrobe Hands and surfaces play a role pic.twitter.com/xxNC1Natwb → https://twitter.com/EricTopol/status/164411262004192871201:09
LjL<Brainstorm> New from r/WorldNews: worldnews: WHO official criticizes China's 'inexcusable' lack of transparency on pandemic's origins → https://old.reddit.com/r/worldnews/comments/12dzybb/who_official_criticizes_chinas_inexcusable_lack/01:13
LjLublix, when i went up to 103, i mostly slept. except in 2016 which was the most recent i had such a fever, i was feeling... just really quite bad. it only lasted one day though01:14
LjL(except i feel that's what kickstarted my on and off malaise)01:14
dmb_yeah, its hard to described, but just doesn't feel good01:16
dmb_like a dizzish feeling, shivery, headachy, muscle achy01:16
LjLdmb_, don't exceed 3000mg a day of acetaminophen (or less, if you've told less, but that's the maximum normal dose outside of hospital settings). it is a useful drug and it is very tolerable in normal amount for short periods, but large amounts or long periods make your liver very sad01:16
LjLjust something to keep in mind01:17
dmb_yeah01:17
dmb_i am alternating between ibuprofen for that reason01:17
LjLi usually don't take more than 1000mg, but i also don't often get your degree of fever, so use common sense, but basically, as long as your fever is safely below "danger" levels, you don't necessarily need to get it lower01:17
dmb_although thanks for letting me know about nausea, now I know its not from covid but meds01:18
LjLwell covid could also cause it, but yeah ibuprofen on an empty stomach is much harder on your stomach, in the short term, than paracetamol is on your liver (in the short term)01:18
ublixi mean, i've had fever as an adult. i've experienced how acetaminophen can pull you back across the line of feeling unwell. just never fever high enough to start thinking about medical attention01:22
ublixbut i know people who have gone into hospital with fever, and had the third party helper account of how they couldn't have done it on their own. i don't recall what the temperatures involved were01:23
ublixi guess i'm curious at what temp you start losing capacity to think and physically act in your own interest01:24
ublixLjL: is this the sort of transparency the WHO is looking for: https://twitter.com/WHO/status/124397219316961689801:29
LjLfor me that would be around 4001:29
ublix^ leaving up a tweet as some sort of mea culpa years after everyone has forgotten we once (were told to) believe it wasn't airborne01:30
LjLublix, for all i know the WHO is looking for their own assholes01:30
LjLwhy do you think it's a mea culpa as opposed to simply not caring about the tweet still being up01:30
ublixi was trying to creatively fit the 3 year old tweet to a notion of transparency :p01:31
LjLMusk gave it transparency by way of allowing readers' context01:32
LjLalthough who the hell knows which readers01:32
LjLbut at least they're right. this time.01:32
LjL(i assume it's only writable by people with a blue checkmark)01:32
LjL"Notes aren't chosen by majority rule. Community Notes identifies notes that are found helpful by and for people with different points of view."01:33
LjL"Twitter doesn't choose what shows up: the people do."01:33
LjLsounds very slightly contradictory01:33
ublixis there a note attached to each note indicating which twitteratu found it useful?01:34
LjLno01:34
LjLthere is just a "Find out more" that lists those two things and another two01:35
LjLit says the "top tags selected by users though"01:36
LjLwhich in this case were01:36
LjLTop tags selected by raters01:36
LjLDirectly addresses the Tweet’s claim01:36
LjLProvides important context01:36
LjLand it tells you that "commendable sky peacock" wrote the note01:36
LjLbut that says nothing because it's an alias, not their actual Twitter name01:36
LjL"Note status computed by open-source algorithm CoreModel (v1.0)"01:37
LjLhttps://communitynotes.twitter.com/guide/en/under-the-hood/ranking-notes#multi-model-note-ranking01:37
LjLenjoy01:37
ublixpeacocks are not skyborne!01:37
ublixbut i suppose it has to be commended for its computer use skills01:37
BrainstormNew from Science Daily: Physicians should be on alert for group A strep as cases experience historic rise, study finds: The U.S. experienced an unprecedented number of group A streptococcal infections in children from October to December of 2022, which should alert physicians to check for the potentially deadly [... want %more?] → https://www.sciencedaily.com/releases/2023/04/230406190358.htm02:08
LjLyaaaaaay all the bugs that were hidden for two years are really feasting now02:10
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Arijit Chakravarty on Twitter: "Nature microbiology paper showing that SC2 infection alters host cell DNA epigenetically. In plain English- there could be *very* long term consequences to covid infections, ones [... want %more?] → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/12e3ndi/arijit_chakravarty_on_twitter_nature_microbiology/03:55
BrainstormNew from BBC Health: Covid origins: Chinese scientists publish long-awaited data: A peer-reviewed study connects the virus with animals sold in the market linked with early cases. → https://www.bbc.co.uk/news/science-environment-6520416904:05
BrainstormUpdates for UAE: +739 cases, +78484 tests since 3 days ago04:12
BrainstormUpdates for Germany: +2412 cases, +132 deaths since 13 hours ago — Syria: +10 cases since 5 days ago05:02
BrainstormNew from r/COVID19: COVID19: Virological characteristics of the SARS-CoV-2 Omicron XBB.1.16 variant → https://old.reddit.com/r/COVID19/comments/12e9kti/virological_characteristics_of_the_sarscov2/06:31
BrainstormUpdates for Morocco: +57 cases since 13 days ago07:00
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): That's basically what happened with @nytimes and this week's Nature article. But after their terribly politicized and infantilized coverage of the actual science of the pandemic, it's not too much of a surprise anymore.(n/n)twitter.com/mbalter/status… → https://twitter.com/michaelzlin/status/164422916710035456108:48
BrainstormNew from r/Coronavirus: Daily Discussion Thread | April 07, 2023: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/12ecqkp/daily_discussion_thread_april_07_2023/09:07
BrainstormNew from Science-Based Medicine: Yes, Schools Were Closed in Sweden: "I had kids in grades 4, 7, and 8 when the pandemic broke out. The latter two were remote for a year and then hybrid for another 6 months or so." The post  first appeared on Science-Based Medicine . → https://sciencebasedmedicine.org/yes-schools-were-closed-in-sweden/09:48
BrainstormUpdates for India: +6050 cases, +14 deaths, +160742 tests since a day ago11:03
BrainstormNew from ProPublica: Homeless Shelters Aren’t Equipped to Deal With New Mexico’s Most Troubled Foster Kids. Police See It for Themselves.: by Ed Williams , Searchlight New Mexico , and Joel Jacobs , ProPublica This story contains depictions of mental illness and [... want %more?] → https://www.propublica.org/article/police-intervene-foster-kids-in-crisis-new-mexico-homeless-shelters11:24
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: In rare cases COVID-19 can cross placenta, causing fetal brain damage, study says | in two cases, the novel coronavirus infection breached the placenta and caused brain damage in the newborns. → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/12ef8yc/in_rare_cases_covid19_can_cross_placenta_causing/11:33
BrainstormNew from r/COVID19: COVID19: Comparing Clinical Outcomes of COVID-19 and Influenza-Induced Acute Respiratory Distress Syndrome: A Propensity-Matched Analysis → https://old.reddit.com/r/COVID19/comments/12efxgq/comparing_clinical_outcomes_of_covid19_and/12:03
BrainstormNew from ProPublica: IRS Strategic Plan Vows to Amp Up Audits of the Rich: by Jeff Ernsthausen ProPublica is a nonprofit newsroom that investigates abuses of power. Sign up to receive our biggest stories as soon as they’re published. Flush with $80 billion in new funding, the IRS is aiming to ramp [... want %more?] → https://www.propublica.org/article/irs-strategic-plan-wealth-tax-dodgers12:22
BrainstormNew from r/Science: science: Surveillance of SARS-CoV-2 at the Huanan Seafood Market | Nature → https://old.reddit.com/r/science/comments/12eg5qw/surveillance_of_sarscov2_at_the_huanan_seafood/12:32
BrainstormNew from Reddit (test): CoronavirusUK: COVID-19 spread in households linked to virus on hands and surfaces | Imperial News | Imperial College London → https://old.reddit.com/r/CoronavirusUK/comments/12egurd/covid19_spread_in_households_linked_to_virus_on/12:41
BrainstormNew from COVID on Twitter: Florian Krammer (@florian_krammer): Great characterization of XBB.1.16 twitter.com/SystemsVirolog… → https://twitter.com/florian_krammer/status/164429276289056358413:01
BrainstormNew from r/COVID19: COVID19: Effectiveness of full (booster) COVID-19 vaccination against severe outcomes and work absenteeism in hospitalized patients with COVID-19 during the Delta and Omicron waves in Greece → https://old.reddit.com/r/COVID19/comments/12ei7y7/effectiveness_of_full_booster_covid19_vaccination/13:39
BrainstormNew from r/COVID19: COVID19: Changes in social behavioral developmental risks in preschool children after the first COVID-19 wave: a prospective longitudinal cohort study → https://old.reddit.com/r/COVID19/comments/12ejnmu/changes_in_social_behavioral_developmental_risks/14:28
BrainstormNew from Reddit (test): Covid2019: In memory of YASMIN PENA (age 18) from Connecticut who died of coronavirus back in 2020   One of the youngest coronavirus victims   (when i first read about her online, it made me take coronavirus much more seriously) → https://old.reddit.com/r/Covid2019/comments/12ekau0/in_memory_of_yasmin_pena_age_18_from_connecticut/14:57
BrainstormUpdates for Russia: +8915 cases, +38 deaths since a day ago15:07
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Seasonality of Respiratory Syncytial Virus — United States, 2017–2023 | MMWR (cdc.gov)The pandemic, introduction of a new virus and the measures to limit his virus effect have had an effect on the virus season, especially Influenza and RSV. → https://twitter.com/Marc_Veld/status/164432708967856128215:17
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Household infection rate was 28·4% for pre-alpha-exposed contacts and 51·8% for alpha-exposed contacts.Primary cases' URT RNA viral load did not correlate with transmission, but was associated with detection of SARS-CoV-2 RNA on their hands. → https://twitter.com/Marc_Veld/status/164433997928242380816:06
BrainstormUpdates for Indonesia: +619 cases, +2 deaths since 22 hours ago — Hong Kong: +98 cases since 22 hours ago16:09
BrainstormNew from COVID on Twitter: (translated) Gunhild Alvik Nyborg (@GANyborg): If you are a healthcare professional and need sources where you can update yourself on what the condition is about, symptoms and possible measures, there are many useful links here. whn.global/long-covid-cli… → https://twitter.com/GANyborg/status/164434214986385817816:17
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): XBB subvariants are starting to crowd out XBB.1.5 in the US without notable change in clinical outcomes. XBB.1.16 is here and not shown by @CDCgov tally, likely the one to overtake in the weeks aheadcovid.cdc.gov/covid-data-tra…nytimes.com/interactive/20… [... want %more?] → https://twitter.com/EricTopol/status/164435490889911910417:06
BrainstormNew from ClinicalTrials.gov: (news): Incidence of Severe COVID-19 Infection in Patients With CLL or B-NHL Who Received Pre-exposure Prophylaxis With Tixagevimab and Cilgavimab in Italy: an Observational Study by the GIMEMA WP on Chronic Lymphoproliferative Disorders and by the FIL → https://clinicaltrials.gov/ct2/show/NCT0580339517:16
BrainstormNew from ClinicalTrials.gov: (news): Building Resilience During the COVID-19 Pandemic: a Randomized Controlled Trial → https://clinicaltrials.gov/ct2/show/NCT0580287517:26
BrainstormNew from r/Coronavirus: Coronavirus: Without other pandemic precautions, hospital mask rules didn't stop COVID spread, study finds → https://old.reddit.com/r/Coronavirus/comments/12eseuo/without_other_pandemic_precautions_hospital_mask/19:24
BrainstormNew from WebMD: Long COVID Hitting Some States, Minorities, Women Harder: The Census Bureau found that while 27% of adults have gotten long COVID, the condition has impacted some states more than others. The proportion of residents hit with long COVID ranged from a low of 18.8% [... want %more?] → https://www.webmd.com/covid/news/20230407/long-covid-hitting-some-states-minorites-women-harder19:53
BrainstormNew from Virology.ws: An mRNA Vaccine to Treat Cancer: by Gertrud U. Rey There are several highly effective vaccines that block infection by human papillomaviruses (HPVs) and thereby prevent the cervical, anogenital, and head and neck cancers caused by these viruses. However, none of these vaccines are [... want %more?] → https://virology.ws/2023/04/07/an-mrna-vaccine-to-treat-cancer/21:21
BrainstormNew from r/Coronavirus: Coronavirus: Births in Italy hit record low in 2022, population shrinks further → https://old.reddit.com/r/Coronavirus/comments/12ex8p7/births_in_italy_hit_record_low_in_2022_population/21:59
BrainstormNew from Contagion Live: The Week's Top Stories: Breakthrough COVID, FDA Approvals, and More: This week's most-read stories discussed unforeseen consequences of the COVID-19 pandemic, including an increase in gastrointestinal diseases and a decrease in childhood asthma diagnoses. → https://www.onclive.com/view/the-week-s-top-stories-breakthrough-covid-fda-approvals-and-more22:09
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Independent replication of some reduction (~25-30%) of #LongCovid with Paxlovid treatment versus controls, among non-hospitalized, vaccinated people with acute Covidmedrxiv.org/content/10.110… @rushin311 @SarjuGanatraMD and colleagues @LaheyMedicine [... want %more?] → https://twitter.com/EricTopol/status/164443783749502156822:38
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Characterization of the growth advantage of XBB.1.16 compared with XBB, XBB.1.5, with its increased fitness that will likely account for it replacing the current variantsbiorxiv.org/content/10.110… by @SystemsVirology → https://twitter.com/EricTopol/status/164444514097784422423:07
BrainstormNew from r/Coronavirus: Coronavirus: Florida health officials removed key data from COVID vaccine report → https://old.reddit.com/r/Coronavirus/comments/12f0q9e/florida_health_officials_removed_key_data_from/23:56

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