libera/##covid-19/ Wednesday, 2023-08-09

BrainstormNew from The Lancet (Online): [Comment] Food: the tuberculosis vaccine we already have: Something marvellous occurred in the USA in the 20th century. Between 1900 and 1944, deaths from tuberculosis plummeted from about 200 people per 100 000 to approximately 50 people per 100 000 [... want %more?] → https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)01321-1/fulltext00:34
BrainstormNew from Virology.ws: Trial By Error: More on the Perplexing Dutch Claim that Null Results for Objective Measures of Physical Activity Are Irrelevant to Fatigue: By David Tuller, DrPH I recently wrote [... want %more?] → https://virology.ws/2023/08/08/trial-by-error-more-on-the-perplexing-dutch-claim-that-null-results-for-objective-measures-of-physical-activity-are-irrelevant-to-fatigue/06:07
Vyrushave the study from Basel been discussed ? Between the beginning of May 2023, and now, 2 top quality papers were introduced07:18
Vyrusthe less respectable one might be perhaps: https://www.science.org/doi/10.1126/sciimmunol.adh345507:18
Vyrusbut the Basel, Switzerland, top quality one is this: https://pubmed.ncbi.nlm.nih.gov/37470105/07:19
Vyrusso swiss professors, without a retractment of the study of course.. found the subclinical injury was at least 1 in 35  in younger people07:19
Vyrusand they emphasised their control group to NOT exercise, otherwise they were under heavy risk of getting a cardiac arrest due to troponin levels07:20
Vyrusthey were not sure about the persistence of the damage done, which is the part even the Pfizer funded studies cannot precisely confirm, due to technology not being up there yet, especially with the subclinical injuries on heart tissue07:21
Vyrusnow on the other hand, first study I referred is actually from way earlier, around 1st of May this year or something07:21
Vyruswhich goes a bit more into the persistence of the heart tissue damage, in comparison with everything else, incl covid itself etc..07:21
Vyrus1 in 35 is astonishing though, just thought I would leave this as a note here. Have a nice day,07:24
BrainstormNew from ECDC: ECDC: Work-life balance during the COVID-19 pandemic: ECDC and Eurofound investigate the impact of selected non-pharmaceutical interventions in the EU → https://www.ecdc.europa.eu/en/news-events/work-life-balance-during-covid-19-pandemic-ecdc-and-eurofound-investigate-impact09:37
BrainstormNew from StatNews: Health: ‘Underwhelming’: NIH trials fail to test meaningful long Covid treatments — after 2.5 years and $1 billion → https://www.statnews.com/2023/08/09/long-covid-nih-trials/10:34
BrainstormNew from BMJ: Long term risk of death and readmission after hospital admission with covid-19 among older adults: retrospective cohort study: AbstractObjectivesTo characterize the long term risk of death and hospital readmission after an index admission with covid-19 among Medicare fee-for-service beneficiaries, and to [... want %more?] → http://www.bmj.com/content/382/bmj-2023-076222.short11:12
BrainstormNew from PubMed: Is particulate or non-particulate steroid the determinant of periarticular injection efficacy for controlling postoperative TKR pain? Network meta-analysis: CONCLUSION: From the available evidence, we concluded that particulate or non-particulate steroid does not significantly affect post-TKR pain management. [... want %more?] → https://pubmed.ncbi.nlm.nih.gov/37555201/12:47
BrainstormNew from Science-Based Medicine: Nasal Sprays To Prevent COVID: The evidence for nasal sprays to prevent COVID is too preliminary to recommend their use. The post  first appeared on Science-Based Medicine . → https://sciencebasedmedicine.org/nasal-sprays-to-prevent-covid/14:04
de-facto%title https://www.npr.org/sections/goatsandsoda/2023/08/08/1192496578/a-new-clue-to-the-reason-some-people-come-down-with-long-covid14:54
Brainstormde-facto, the URL could not be loaded14:54
de-factotitle "A new clue to the reason some people come down with long COVID"14:55
de-facto%title https://www.medrxiv.org/content/10.1101/2023.06.29.23292056v114:55
Brainstormde-facto: From www.medrxiv.org: Genome-wide Association Study of Long COVID | medRxiv14:55
Vyrusthese past 3 years still look so surreal to me, buying a PAPR and a hazmat suit is still in my todo list LOL15:09
Vyrusinteresting study de-facto thx, nice read. I was recently helping radiologists in reddit interpret a young girl's lung CT window scans, getting covid can seriously affect the lungs in serious cases - it was a bit terrifying to be able to read others' CTs, the ones that got covid induced pneumonia15:12
BrainstormNew from Retraction Watch: Colombia drug regulator halts clinical research at US-funded facility: Following an inspection earlier this month, Colombia’s FDA has suspended all human research at a facility that until this summer had been receiving U.S. funding to [... want %more?] → https://retractionwatch.com/2023/08/09/colombia-drug-regulator-halts-clinical-research-at-us-funded-facility/15:31
undefined_bobVyrus: are those the images with this fuzzy glas like clouds in them?15:35
BrainstormNew from StatNews: Meet the scientists trying to stop the next global pandemic from starting in Africa: “Everybody in the world should be a sentinel, a sentinel not only for his own immediate community, for his own country — but a sentinel for the globe.” → https://www.statnews.com/2023/08/09/happi-sabeti-sentinel-geneticists-global-pandemic-africa/16:38
BrainstormNew from StatNews: Nonprofit naloxone maker celebrates FDA approval by donating 200,000 doses: Naloxone is viewed as a critical way of fighting the opioid epidemic. But its high price has hurt efforts to distribute it en masse. → https://www.statnews.com/2023/08/09/naloxone-harm-reduction-therapeutics/17:35
BrainstormNew from Contagion Live: The Case for Revaccinating Against HBV After Eradicating HCV: Hepatitis B vaccine non-responders with chronic HCV infection were likely to respond and gain protection against HBV after HCV treatment. → https://www.contagionlive.com/view/the-case-for-revaccinating-against-hbv-after-eradicating-hcv18:33
BrainstormNew from StatNews: Study mapping how SARS-CoV-2 disrupts mitochondria suggests a cause for long Covid: The SARS-CoV-2 virus hijacks our cellular power plants known as mitochondria. A new study hypothesizes that could potentially explain long Covid. → https://www.statnews.com/2023/08/09/long-covid-mitochondria-sars-cov-2/20:10
ublx^ LjL that's a bit mind boggling20:44
ublxfascinating, though20:45
Brainstorm(Matrix) <L​jL> Wish I could still see any of these things as fascinating21:14
ublxit suggested sars2 diverts mitochondrial functional output to better facilitate viral replication21:21
ublxdiabolical more than fascinating i guess21:22
BrainstormNew from StatNews: CDC director overhauls leadership of center that oversaw response to Covid-19: The new director of the CDC, Mandy Cohen, is overhauling the leadership of the CDC center that led the agency’s Covid-19 response. → https://www.statnews.com/2023/08/09/cdc-director-overhaul-center-oversaw-covid-19-response/23:11
mrdatawhat is going on with Brainstorm23:53

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