libera/##covid-19/ Friday, 2023-12-01

BrainstormNew from Nature Vaccines: Felipe Lelis et al.: Safety, immunogenicity and efficacy of an mRNA-based COVID-19 vaccine, GLB-COV2-043, in preclinical animal models → https://www.nature.com/articles/s41598-023-46233-608:30
BrainstormNew from StatNews: STAT+: Pfizer to halt development of its twice-daily oral obesity drug, following disappointing trial: Pfizer said Friday it was stopping development of a twice-daily oral obesity medication, a blow to the company’s efforts to compete in the booming weight loss field. → https://www.statnews.com/2023/12/01/pfizer-obesity-danuglipron/12:49
BrainstormNew from r/Coronavirus: Coronavirus: Study estimates 2 COVID vaccine doses 40% effective against emergency, hospital care in young kids → https://old.reddit.com/r/Coronavirus/comments/188aizl/study_estimates_2_covid_vaccine_doses_40/13:27
BrainstormNew from EMA: What's new: Document: COVID-19 vaccines - Safety update: 8 December 2022 → https://www.ema.europa.eu/documents/covid-19-vaccine-safety-update/covid-19-vaccines-safety-update-8-december-2022_.pdf13:37
BrainstormNew from EMA: What's new: Document: COVID-19 lessons learned: Joint report on the response to the public health emergency → https://www.ema.europa.eu/documents/report/covid-19-lessons-learned-joint-report-response-public-health-emergency_en.pdf13:57
BrainstormNew from r/COVID19: Monthly Scientific Discussion Thread - December 2023: This monthly thread is for scientific discussion pertaining to COVID-19. Please post questions about the science of this virus and disease here to collect them for others and clear up post space for [... want %more?] → https://old.reddit.com/r/COVID19/comments/188bb9n/monthly_scientific_discussion_thread_december_2023/14:07
BrainstormNew from BMJ: Malaria: Climate change poses “substantial risk to progress,” WHO warns: A “substantial pivot” is needed to get the fight against malaria back on track after a pause in progress, the World Health Organization has warned.1There were an estimated 249 million malaria cases globally in 2022—16 million more [... want %more?] → http://www.bmj.com/content/383/bmj.p2848.short14:26
BrainstormNew from BBC Health: (news): Covid inquiry: Some local leaders put politics ahead of public health, says Hancock → https://www.bbc.co.uk/news/uk-politics-6758776315:04
BrainstormNew from StatNews: Pharma: STAT+: Pharmalittle: Pfizer halts development of twice-daily obesity pill; Supreme Court to review Purdue bankruptcy deal → https://www.statnews.com/pharmalot/2023/12/01/pfizer-obesity-lilly-novo-wegovy-covid19-vaccine-paxton-astrazeneca-intas-fda-sec-purdue-opioids-supreme-court/15:14
BrainstormNew from StatNews: Johnson & Johnson bets heavy on AI-driven drug discovery: Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your inbox. Today we talk about Pfizer's obesity woes, how J&J… → https://www.statnews.com/2023/12/01/biotech-news-johnson-johnson-pfizer-car-t-adc-ai-purdue-novo-nordisk/15:34
BrainstormNew from ECDC: Communicable disease threats report, 26 November - 2 December 2023, week 48: This issue of the ECDC Communicable Disease Threats Report (CDTR) covers the period 19 - 25 November 2023 and includes updates on human infection with influenza [... want %more?] → https://www.ecdc.europa.eu/en/publications-data/communicable-disease-threats-report-26-november-2-december-2023-week-4816:03
BrainstormNew from r/WorldNews: worldnews: HIV infection rates reach epidemic levels in 19 Russian regions → https://old.reddit.com/r/worldnews/comments/188e0u1/hiv_infection_rates_reach_epidemic_levels_in_19/16:23
BrainstormNew from Marc Veldhoen on Mastodon: (news): The data is derived from plasma obtained 7 to 13 days (mean: 9.7 days) after vaccination with the XBB.1.5 S mRNA booster and used for in vitro pseudovirus neutralisation assays. The first response you would expect within this time are memory B cells, not naive B cells. → https://mastodon.online/@marc_veld/11150584799682674516:33
BrainstormNew from Marc Veldhoen on Mastodon: (news): Of additional interest, no difference between Pfizer or Moderna vaccines. → https://mastodon.online/@marc_veld/11150596175314990517:02
BrainstormNew from r/Coronavirus: Coronavirus: Gray Matter Thickness and Subcortical Nuclear Volume in Men After SARS-CoV-2 Omicron Infection (Reduced) → https://old.reddit.com/r/Coronavirus/comments/188fdl2/gray_matter_thickness_and_subcortical_nuclear/17:12
BrainstormNew from r/Coronavirus: Coronavirus: CDC Warns of BA.2.86 'Pirola' Variant Rising in US → https://old.reddit.com/r/Coronavirus/comments/188hm8o/cdc_warns_of_ba286_pirola_variant_rising_in_us/19:08
LjLi think my gray matter is suffering injuries from just reading these abstracts about it19:11
LjLwhich is probably why smarter people have stopped doing that and this channel is largely empty19:11
BrainstormNew from Marc Veldhoen on Mastodon: (translated) (**news): This whole honest assertion: We will always older, man stay it best/best such largely possibly in her house live, as is a to briefly at **verzorgingshuizen. But #someone makes as **COVID-19 serums from  ‍   → https://mastodon.online/@marc_veld/11150661632794960019:47
de-factoVariants come and go, they always are going to rise and fall, thats normal20:28
de-factothe question is more do they make more problems than their predecessors? how much immune escape do they have? whats their potential for severity?20:29
de-factoif its just another one similar to the ones before it just means the natural endemic cycle for new variants replacing their predecessors20:29
de-factoBA.2.86 also is rising in Germany btw20:33
de-factoBA.2.86.1 and JN.120:34
de-factohttps://public.data.rki.de/t/public/views/IGS_Dashboard/DashboardSublineages?%3Aembed=y&%3AisGuestRedirectFromVizportal=y20:35
LjLde-facto, i wasn't referring to the variant message, but to <Brainstorm> New from r/Coronavirus: Coronavirus: Gray Matter Thickness and Subcortical Nuclear Volume in Men After SARS-CoV-2 Omicron Infection (Reduced) → https://old.reddit.com/r/Coronavirus/comments/188fdl2/gray_matter_thickness_and_subcortical_nuclear/20:41
de-factoyuck20:45
LjLthere's a discussion of it here https://old.reddit.com/r/COVID19/comments/187nu6s/gray_matter_thickness_and_subcortical_nuclear/ as well20:47
LjLnot a very long discussion, i'm guessing r/covid19 has banned... most people20:47
de-factoi honestly wonder how that possibly could be related to aggression levels that we may have observed several times during the pandemic20:51
de-factolike could it trigger a kind of immune response on epitopes that also can be found on the surface of brain structures and therefore have trigger an inflammatory response in the brain that leads to some kind of damage that also comes with certain behavior patterns?20:53
BrainstormNew from r/COVID19: COVID19: True prevalence of long-COVID in a nationwide, population cohort study → https://old.reddit.com/r/COVID19/comments/188lclx/true_prevalence_of_longcovid_in_a_nationwide/21:25
BrainstormNew from Contagion Live: The Latest In Infectious Disease: This week's news includes a Massachusetts hospital facing a lawsuit for potential HIV and hepatitis exposure, a study shows reduced mortality rates in combining vancomycin and cefazolin in patients with bloodstream infections, a PCR-based rapid [... want %more?] → https://www.contagionlive.com/view/the-latest-in-infectious-disease22:16
BrainstormNew from Reddit (test): How can I find out why I’ve been invited for booster?: For the past two years I’ve been getting spammed by the NHS telling me their records show I’m eligible for the booster. I’m not aware of any reason why this should be the case so I’m [... want %more?] → https://old.reddit.com/r/CoronavirusUK/comments/188mmfy/how_can_i_find_out_why_ive_been_invited_for/23:44

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