| Brainstorm | New from r/Science: science: Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses → https://old.reddit.com/r/science/comments/18t6t26/parainfectious_brain_injury_in_covid19_persists/ | 01:39 |
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| Brainstorm | New from r/COVID19: COVID19: BNT162b2 XBB1.5-adapted Vaccine and COVID-19 Hospital Admissions and Ambulatory Visits in US Adults → https://old.reddit.com/r/COVID19/comments/18t9owo/bnt162b2_xbb15adapted_vaccine_and_covid19/ | 01:49 |
| Brainstorm | New from StatNews: First Opinion: Opinion: Buprenorphine, autism diagnoses, and long Covid: the most-read First Opinion essays of 2023 → https://www.statnews.com/2023/12/29/buprenorphine-x-waivers-autism-long-covid-first-opinion-2023/ | 10:39 |
| Brainstorm | New from ProPublica: The Most-Read ProPublica Stories of 2023: by ProPublica ProPublica is a nonprofit newsroom that investigates abuses of power. Sign up to receive our biggest stories as soon as they’re published. ProPublica has been producing and delivering the news digitally for 15 years, and while [... want %more?] → https://www.propublica.org/article/propublica-most-read-stories-2023 | 11:18 |
| Brainstorm | New from BMJ: Intersectionality in health equity research: The covid-19 pandemic highlighted deep rooted societal inequities and their causes because of its disproportionate effects on certain groups, including people living in deprived areas and ethnic minorities.1 Most of the early research into covid-19 focused on single [... want %more?] → http://www.bmj.com/content/383/bmj.p2953.short | 11:56 |
| Brainstorm | New from ProPublica: Our Year in Visual Journalism: by ProPublica’s Visual Storytelling Department ProPublica is a nonprofit newsroom that investigates abuses of power. Sign up to receive our biggest stories as soon as they’re published. Photo illustration by Hisham Akira Bharoocha, photography by Kathleen [... want %more?] → https://www.propublica.org/article/visual-journalism-2023 | 12:25 |
| Brainstorm | New from r/Science: science: Common indoor air pollutants could affect creativity: scientists found that high levels of volatile organic compounds – gases released from products such as detergents, pesticides, perfumes, aerosol sprays, paint – affected a study participants’ creativity → https://old.reddit.com/r/science/comments/18tkzdg/common_indoor_air_pollutants_could_affect/ | 12:45 |
| Brainstorm | New from r/COVID19: COVID19: Fox Sports Host Nick Wright Gets Jabbed On Social Media After Rant Calling Aaron Rodgers ‘Most Disingenuous Athlete Of My Lifetime’ → https://old.reddit.com/r/COVID19/comments/18to8fy/fox_sports_host_nick_wright_gets_jabbed_on_social/ | 15:29 |
| Brainstorm | New from r/COVID19: COVID19: Continued selection on cryptic SARS-CoV-2 observed in Missouri wastewater → https://old.reddit.com/r/COVID19/comments/18tomi4/continued_selection_on_cryptic_sarscov2_observed/ | 15:48 |
| Brainstorm | New from Eric Topol on Mastodon: (news): New data for the "updated" (XBB.1.5) booster → https://mstdn.social/@erictopol/111664707690285890 | 17:54 |
| Brainstorm | New from r/COVID19: COVID19: Predicted risk of heart failure pandemic due to persistent SARS-CoV-2 infection using a three-dimensional cardiac model → https://old.reddit.com/r/COVID19/comments/18tsahw/predicted_risk_of_heart_failure_pandemic_due_to/ | 18:32 |
| LjL | de-facto, good that your choice of filling yourself with green tea is confirmed good by studies :) | 19:27 |
| LjL | I have some trouble looking at this channel lately. Most of the studies that pop up from Brainstorm are just too dreadful. | 19:28 |
| de-facto | lol i dont drink that much of Green Tea though | 19:44 |
| de-facto | %title https://www.medrxiv.org/content/10.1101/2023.12.24.23300512v1 | 21:14 |
| Brainstorm | de-facto: From www.medrxiv.org: BNT162b2 XBB1.5-adapted Vaccine and COVID-19 Hospital Admissions and Ambulatory Visits in US Adults | medRxiv | 21:14 |
| LjL | de-facto, that's pretty disappointing. XBB vaccine only reduces *hospitalization* to 37% (we were told so many times that, okay, the vaccine doesn't protect much against *infection*, but it's very effective against *hospitalization* and severe outcomes - this does not seem VERY effective! it helps, but...) and then those who didn't get the XBB vaccine but got all the previous ones " did not show significantly reduced risk of COVID-19 outcomes, including hospital | 21:29 |
| LjL | admission" :( | 21:29 |
| de-facto | well it probably depends on the immunologic history, e.g. today with the T-cells mostly already knowing some epitopes of previous SARS-CoV-2 variants the hospitalization risk most likely is lowered in comparison to a population with mostly naive immune systems | 21:32 |
| de-facto | hence we can ask the question what kind of people are selected for still ending up in hospital with COVID today (with mostly partially immuno-competent populations) in comparison to the start of the pandemic (with mostly immuno-naive populations) | 21:33 |
| de-facto | my suspicion (without data though) would be that today its a different selection of people that end up hospitalized with COVID and this group may have some property that also can make it less responsive to vaccine protection, but that is just speculation | 21:34 |
| LjL | i'm not sure that all matters so much... it's a substantial amount of people, who cares if they're somehow "weak"? it's a huge problem | 21:46 |
| LjL | and if this paper's conclusions about people who ARE vaccinated but haven't gotten the latest XBB are right... it says there is NO difference in hospitalization outcomes compared to the unvaccinated. so, what are everyone's T cells doing? it goes for *everyone*, not just a subset of people | 21:47 |
| de-facto | unvaccinated does not mean naive T-cells though | 21:51 |
| de-facto | the largest majority of people are not immuno-naive anymore, most are both, vaccinated and recovered, some suffer from long lasting problems and probably (to be investigated) fewer than in a naive population end up hospitalized, even fewer with XBB.1.5 immuno-competence | 21:52 |
| de-facto | with the current JN.1 and BA2.86 in circulation that is | 21:54 |
| Brainstorm | New from Marc Veldhoen on Mastodon: (news): The immune system is a super complex network of trillions of cells. What you can do is educate your immune system to rapidly take action against specific pathogens. This is achieved using vaccines. → https://mastodon.online/@marc_veld/111665910574208849 | 22:51 |
| Brainstorm | New from Marc Veldhoen on Mastodon: (news): What this report shows is that among the select group of people that did, for health reasons, take the additional XBB.1.5 booster, in the only 30-day follow-up, had additional benefits. One is a reduction of infections themselves! → https://mastodon.online/@marc_veld/111666060137318212 | 23:30 |
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