libera/##covid-19/ Friday, 2023-03-17

BrainstormNew from The Lancet (Online): Roland Tschismarov, Pierre Van Damme, Clara Germain, Ilse De Coster, Mathieu Mateo, Stephanie Reynard, Alexandra Journeaux, Yvonne Tomberger, Kanchanamala Withanage, Denise Haslwanter, Katherine Terler, Sabrina Schrauf, Matthias Müllner, Erich Tauber, Katrin [... want %more?] → https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)00048-X/fulltext00:37
BrainstormNew from StatNews: Polio cases derived from new oral vaccine reported for first time: Experts have long understood that a new polio vaccine developed to try to minimize the risks associated with the oral polio vaccine made by Albert Sabin might also cause the… → https://www.statnews.com/2023/03/16/polio-cases-derived-from-new-oral-vaccine-reported-for-first-time/00:46
BrainstormNew from r/Coronavirus: The Strongest Evidence Yet That an Animal Started the Pandemic: The Atlantic magazine has an article that they have the strongest evidence that an animal created the coronavirus at the Huanan seafood market. They say that the samples that were [... want %more?] → https://old.reddit.com/r/Coronavirus/comments/11tb2fm/the_strongest_evidence_yet_that_an_animal_started/02:43
BrainstormUpdates for Guatemala: +428 cases since a day ago03:09
BrainstormNew from r/COVID19: COVID19: Potential recombination between SARS-CoV-2 and MERS-CoV: calls for the development of Pan-CoV vaccines → https://old.reddit.com/r/COVID19/comments/11tf4hs/potential_recombination_between_sarscov2_and/04:01
BrainstormUpdates for Pakistan: +133 cases since 23 hours ago05:01
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): If you have no idea about how specific immune cell are. You really think a COVID-19 vaccine protect overal against ageing, car accidents and cancer? Wow!!   you better say stupid things anonymously. Oh you do! twitter.com/IsZomg/status/… pic.twitter.com/FAJGoTmsaR → https://twitter.com/Marc_Veld/status/163660667239424409806:56
BrainstormNew from r/COVID19: COVID19: Israel on high alert as New COVID-19 variant is identified → https://old.reddit.com/r/COVID19/comments/11tj9l7/israel_on_high_alert_as_new_covid19_variant_is/07:34
BrainstormNew from r/Coronavirus: Daily Discussion Thread | March 17, 2023: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/11tjq49/daily_discussion_thread_march_17_2023/08:03
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Unearthed genetic sequences from China market may point to animal origin of COVID-19French scientist finds previously undisclosed data from Chinese research teamscience.org/content/articl… → https://twitter.com/Marc_Veld/status/163663301299665716008:43
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): The viruses from the market shared nucleotide identity of 99.980% to 99.993% with the human isolate HCoV/Wuhan/IVDC-HB-01. → https://twitter.com/Marc_Veld/status/163663403657039872208:53
BrainstormUpdates for Belgium: +18083 cases, +71 deaths, +45182 tests since 7 days ago — India: +796 cases, +5 deaths, +101160 tests since a day ago — North Macedonia: +330 cases, +2 deaths since 21 days ago — Germany: +7680 cases, +119 deaths since a day ago09:11
BrainstormNew from r/Science: science: Study of 1.65M COVID Vaccine Doses Finds Rare "Myocarditis" Generally Mild—More Than Half of Patients Didn't Need to be Hospitalized → https://old.reddit.com/r/science/comments/11tkyc1/study_of_165m_covid_vaccine_doses_finds_rare/09:42
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Today's breathless @nytimes story: animal cages previously known to have SARSCoV2 DNA on them now known to have animal DNA on them. → https://twitter.com/michaelzlin/status/163666149099557273710:43
BrainstormNew from PubMed: Use of mesenchymal stem cell therapy in COVID-19 related strokes: Coronavirus disease 2019 (COVID-19) has affected a broad demographics, eliciting a more significant effect on specific groups such as males, African Americans, and Hispanic minorities. Treatment of COVID-19 often requires antiviral drugs or [... want %more?] → https://pubmed.ncbi.nlm.nih.gov/36926703/12:02
BrainstormNew from COVID on Twitter: Nationale Akademie der Wissenschaften Leopoldina (@Leopoldina): Together with epidemiologist Michael Edelstein @epi_michael, immunologist Akiko Iwasaki @VirusesImmunity and microbiologist Marc Lecuit @BIUPasteur, here @C_Scheibenbogen discusses the latest research on long-term consequences [... want %more?] → https://twitter.com/Leopoldina/status/163667781366629990412:12
BrainstormNew from ProPublica: Regulatory Failure 101: What the Collapse of Silicon Valley Bank Reveals: by Jesse Eisinger ProPublica is a nonprofit newsroom that investigates abuses of power. Sign up to receive our biggest stories as soon as they’re published. This story is exempt from our Creative [... want %more?] → https://www.propublica.org/article/silicon-valley-bank-failure-fdic-fed-failure12:21
BrainstormNew from ECDC: Weekly COVID-19 country overview: This weekly report provides an overview of the epidemiological situation of the COVID-19 pandemic and COVID-19 vaccine rollout by country. → https://www.ecdc.europa.eu/en/news-events/weekly-covid-19-country-overview12:32
BrainstormNew from Reddit (test): nCoV: Global COVID Cases For 17MAR23 → https://old.reddit.com/r/nCoV/comments/11tp4s5/global_covid_cases_for_17mar23/13:11
BrainstormNew from r/Science: science: A novel cancer therapeutic, combining antibody fragments with molecularly engineered nanoparticles, permanently eradicated gastric cancer in treated mice, a multi-institutional team of researchers found → https://old.reddit.com/r/science/comments/11tpk5v/a_novel_cancer_therapeutic_combining_antibody/13:31
pwr22LjL: it's a shame we don't have more data / research on it13:44
ublxpwr22: do i recall correctly.. was it yourself who once some while ago confessed to being fond of brazil nuts?13:51
pwr22Lol, it wasn't me13:51
ublxah ok. nvm. someone did13:51
BrainstormNew from Contagion Live: CDI Risk Higher for People with COVID-19: The investigators found the risk of hospital-acquired Clostridioides difficile (CDI) infection increased when a hospital switched to serving only coronavirus disease 2019 patients. → https://www.onclive.com/view/cdi-risk-higher-for-people-with-covid-1913:52
ublxi recently looked at selenium content of brazil nuts (had been oblivious before) and learned: adult RDA for selenium ~55µg/day; upper tolerable limit ~400µg/day; selenium content of ONE brazil nut ~70-90µg! and selenium toxicity is no joke13:55
ublxwonder who my fellow brazil nut fan was and whether they're still alive :\13:56
pwr22He he, the upper limit for those sorts of biologically relevant trace metals tends to be set conservatively and something you need to eat a lot of to really suffer from13:58
pwr22Though I don't off the top of my head recall that to be true for sure about selenium13:59
pwr22I would imagine it must be the case though, else brazil nuts would not be considered a food surely 😛 ?13:59
ublxwell last summer i ate handfuls of them for lunch and i'm not dead; i did however seek medical attention for generalised malaise that lead to an unrelated diagnosis but which investigation did discover a deranged biochemical marker you'd expect from selenium overconsumption14:02
ublxhere's an interesting article the moral of which might be be careful of general supplements being less rigorously regulated than medicinal pharmaceuticals: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225252/ "Acute Selenium Toxicity Associated With a Dietary Supplement"14:03
pwr22That's interesting! Did they detect high levels of selenium and was the marker very specific?14:03
pwr22Seems like it could be not ideal to eat a bunch of them everyday 😧14:03
ublxin which "200 times the labeled concentration of selenium" was discovered in the supplement (lead to an outbreak of toxicity cases)14:03
pwr22Zinc is another interesting one, in some cases taking high doses acutely is actually good14:04
pwr22But if you take the dose a lot of supplements have consistently, you could build up a problematic accumulation 😧14:04
pwr22ublx: lol, that's insane14:04
ublxno they had no reason to look for selenium; i mentioned it months later as an explanation for the biochemical marker, having stumbled on the brazil nut selenium content entirely by accident14:04
ublxno the marker was not specific14:05
ublxfor selenium; but my rate of brazil nut abuse strongly suggests to me it was a factor14:06
pwr22He he14:07
pwr22Maybe we could homogenise you then check your total selenium concentration? (warning: may cause adverse health effects)14:07
ublxthat article i linked remarks that metabolism disposes of selenium rather slowly, so i might yet be a useful selenium reservoir!14:08
BrainstormUpdates for Russia: +12915 cases, +35 deaths since 23 hours ago14:10
darsieI made 60 µg selenium/drop as selenous acid because Brazil nuts have highly variable Se content, so I might get too little or too much from them.14:11
BrainstormNew from COVID on Twitter: Centre for Epidemic Response & Innovation (CERI) (@ceri_news): We love the fresh perspectives and passion that our international fellows bring to the CERI team!So great having Dr. Padane @AbdouPadane with us. twitter.com/Tuliodna/statu… → https://twitter.com/ceri_news/status/163671503406679655914:22
BrainstormNew from StatNews: Pharma: STAT+: Pharmalittle: Sanofi cuts price on a popular insulin by 78%; Califf criticizes insurers for doing too little on drug research → https://www.statnews.com/pharmalot/2023/03/17/sanofi-insulin-califf-insurers-sarepta-duchenne/14:32
BrainstormNew from BMJ Open: Cohort profile: InfCareHIV, a prospective registry-based cohort study of people with diagnosed HIV in Sweden: Purpose The Swedish InfCareHIV cohort was established in 2003 to ensure equal and effective care of people living with HIV (PLHIV) and enable long-term follow-up. InfCareHIV functions equally [... want %more?] → http://bmjopen.bmj.com/cgi/content/short/13/3/e06968815:32
BrainstormNew from BMJ Open: Trends in antineoplastic drug use, cost and prescribing patterns among patients with lung cancer in nine major cities of China, 2016-2020: a retrospective observational study based on inpatient and outpatient hospital data: Objectives It is unclear whether the use of antineoplastic drugs for patients [... want %more?] → http://bmjopen.bmj.com/cgi/content/short/13/3/e06964515:42
BrainstormNew from Politico: Aid and development: WHO: Raccoon dog data give clues to COVID origin — but no definitive answer → https://www.politico.eu/article/who-raccoon-dog-data-china-covid-origin-wuhan-market-genetic-sample/15:52
BrainstormUpdates for Nepal: +6 cases since a day ago16:03
BrainstormNew from ClinicalTrials.gov: (news): To Explore the Protective Effect of SARS-CoV-2 Vaccination on Cancer Patients Infected With SARS-CoV-2 → https://clinicaltrials.gov/ct2/show/NCT0577417116:13
BrainstormNew from ClinicalTrials.gov: (news): Evaluation of COVID-19 Immune Barrier and Reinfection Risk → https://clinicaltrials.gov/ct2/show/NCT0577409316:33
BrainstormNew from ClinicalTrials.gov: (news): Short-term Effects of Transdermal Estradiol on Female COVID-19 Patients → https://clinicaltrials.gov/ct2/show/NCT0577440516:42
BrainstormNew from ClinicalTrials.gov: (news): Evaluation of the Impact of the Anti COVID-19 Vaccination Campaign Addressed to the Employees of an Italian Hospital. → https://clinicaltrials.gov/ct2/show/NCT0577441816:52
BrainstormNew from WebMD: It's (Finally) Time to Stop Calling It a Pandemic: Experts: Many experts say we have entered a new phase as health care crises seem to have quieted and the public has moved on to endemic behavior. Others say it's too soon to label COVID trajectory predictable. → https://www.webmd.com/covid/news/20230317/time-to-stop-calling-it-a-pandemic17:12
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): All remains quiet on the new variant frontcovid.cdc.gov/covid-data-tra… pic.twitter.com/uw5AQ1ftNY → https://twitter.com/EricTopol/status/163677895255459020818:21
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The vital role of patients and the public in guiding #LongCovid researchnature.com/articles/s4159… @NatureMedicine by @AshRouten and colleagues pic.twitter.com/6qif9SHjUB → https://twitter.com/EricTopol/status/163678328485959270418:41
BrainstormNew from COVID on Twitter: Ulrich Elling (@EllingUlrich):    Representative genomic surveillance of SARS-CoV-2 in Austria week 11, 2023 across most regions. Current analysis includes samples until March 9th allowing faithful nowcasting. A collaboration of #AGES @agesnews and @IMBA_Vienna/@oeaw. 1/6 pic.twitter.com/V0rS0mjlN2 → https://twitter.com/EllingUlrich/status/163678467098869761118:51
BrainstormNew from NPR Science: WHO calls on China to share data on raccoon dog link to pandemic. Here's what we know: Data was released briefly, then rescinded. As NPR reported previously, there is already strong evidence pointing to these [... want %more?] → https://www.npr.org/sections/goatsandsoda/2023/03/17/1164226694/who-calls-on-china-to-share-data-on-raccoon-dog-link-to-pandemic-heres-what-we-k19:20
BrainstormNew from New Scientist: Covid-19 may have started in raccoon dogs, new DNA evidence shows: Swabs taken from the suspected seafood market in Wuhan contain both the coronavirus and DNA from raccoon dogs and other animals → https://www.newscientist.com/article/2365055-covid-19-may-have-started-in-raccoon-dogs-new-dna-evidence-shows/19:49
BrainstormNew from Contagion Live: COVID-19 News Update: The Top 5 Stories This Week: Yesterday, the FDA took a major step toward officially approving Paxlovid. Catch up on this story and the other top COVID-19 news updates from the past week. → https://www.onclive.com/view/covid-19-news-update-the-top-5-stories-this-week20:38
BrainstormNew from Reddit (test): CoronavirusUK: Coronavirus (COVID-19) Infection Survey, UK: 16 March 2023 → https://old.reddit.com/r/CoronavirusUK/comments/11u2ah5/coronavirus_covid19_infection_survey_uk_16_march/21:16
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: 5 residents dead as COVID-19 outbreak hits Cape Cod nursing home → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/11u2uw7/5_residents_dead_as_covid19_outbreak_hits_cape/21:36
BrainstormUpdates for Montenegro: +64 cases, +539 tests since 22 hours ago — Cuba: +12 cases since a day ago22:05
BrainstormUpdates for Italy: +23732 cases, +212 deaths, +452747 tests since 6 days ago — Lebanon: +223 cases, +3 deaths since a day ago — Ethiopia: +33 cases since a day ago — Myanmar: +11 cases, +4045 tests since a day ago23:07
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: "COVID-somnia" and the impact of long COVID on sleep - CBS News → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/11u6dfh/covidsomnia_and_the_impact_of_long_covid_on_sleep/23:42

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