libera/##covid-19/ Tuesday, 2023-12-05

BrainstormNew from Marc Veldhoen on Mastodon: (news): Pandemics and epidemics have this effect, laying bare underlying health issues after the peak of infection, not in the oldest, but largely middle age, and a contribution even from the young. → https://mastodon.online/@marc_veld/11152467799149313000:18
BrainstormNew from Ars Technica: Health: Texas sues Pfizer with COVID anti-vax argument that is pure stupid → https://arstechnica.com/?p=198850700:56
BrainstormNew from BBC Health: Humiliated Covid whistleblower says boss tried to 'break' her: A senior doctor gives her first interview since being awarded a record £3.2m payout at a tribunal. → https://www.bbc.co.uk/news/health-6756549802:41
BrainstormNew from r/COVID19: COVID19: People With Severe Mental Illness Experienced Increased COVID-19 Mortality → https://old.reddit.com/r/COVID19/comments/18b2ld1/people_with_severe_mental_illness_experienced/04:35
BrainstormNew from r/COVID19: COVID19: Severe mental illness, race/ethnicity, multimorbidity and mortality following COVID-19 infection: nationally representative cohort study | The British Journal of Psychiatry | Cambridge Core → https://old.reddit.com/r/COVID19/comments/18b6ax3/severe_mental_illness_raceethnicity/08:04
TimvdeAre the vaccines still updated?08:46
TimvdeMy mom got a booster a month ago or so, she caught COVID now and is pretty sick :/08:46
Timvde(She did also get a flu vaccine by the end of last week, could that have an impact?)08:47
BrainstormNew from StatNews: Is the flu shot market a slam dunk for mRNA vaccines? Experts aren’t so sure: Pfizer, Moderna, GSK, and Sanofi Pasteur all working on mRNA flu shots. But how well-suited is the technology for influenza vaccines? → https://www.statnews.com/2023/12/05/flu-shots-mrna-vaccines/10:39
BrainstormNew from PubMed: Anxiety in a COVID-19 school year context: three-way longitudinal study on Slovenian adolescent sample: BACKGROUND AND OBJECTIVES: We investigated the trajectories of anxiety, general anxiety and more specifically COVID-19 anxiety in the period of school closure in Slovenia using a longitudinal design with three [... want %more?] → https://pubmed.ncbi.nlm.nih.gov/38049932/11:07
BrainstormNew from ProPublica: “Someone Tell Me What to Do”: by Lomi Kriel and Lexi Churchill , ProPublica and The Texas Tribune , and Jinitzail Hernández , The Texas Tribune The children hid. They dropped to the floor, crouching under desks and countertops, far from the windows. They lined up [... want %more?] → https://www.propublica.org/article/uvalde-officer-student-trainings-mass-shootings12:15
BrainstormNew from PubMed: Anxiety in a COVID-19 school year context: three-way longitudinal study on Slovenian adolescent sample: BACKGROUND AND OBJECTIVES: We investigated the trajectories of anxiety, general anxiety and more specifically COVID-19 anxiety in the period of school closure in Slovenia using a longitudinal design with three [... want %more?] → https://pubmed.ncbi.nlm.nih.gov/38049932/12:24
BrainstormNew from r/Coronavirus: Coronavirus: Slow COVID-19 booster rollout cost thousands of lives, new study says → https://old.reddit.com/r/Coronavirus/comments/18ba9zz/slow_covid19_booster_rollout_cost_thousands_of/12:56
BrainstormNew from r/Coronavirus: Coronavirus: Small study finds brain alterations after COVID Omicron infection → https://old.reddit.com/r/Coronavirus/comments/18babll/small_study_finds_brain_alterations_after_covid/13:05
BrainstormNew from StatNews: STAT+: J&J to emphasize cancer drugs and stop much of its vaccine research: Eight months into his tenure, Johnson & Johnson’s R&D chief is putting a big emphasis on medicines for cancer, treatment-resistant depression, and autoimmune disease. → https://www.statnews.com/2023/12/05/jj-to-emphasize-cancer-drugs-and-stop-much-of-its-vaccine-research/13:25
BrainstormNew from r/COVID19: COVID19: Severe mental illness, race/ethnicity, multimorbidity and mortality following COVID-19 infection: nationally representative cohort study → https://old.reddit.com/r/COVID19/comments/18bcq28/severe_mental_illness_raceethnicity/15:12
de-factoTimvde, yes i think vaccine ubdate for XBB.1.5 e.g. https://www.yalemedicine.org/news/updated-covid-vaccine-10-things-to-know15:32
de-factodo you happen to know which one she got (out of curiosity)15:32
de-factohope she is getting better soon, i dont think the flu vaccine plays a role, the immune system has more than enough resources to deal even with multiple vaccines or even disease at once15:33
de-factothe COVID epitopes are much more exposed anyhow when she got it, hence will be the main target of the immune response15:34
dTaleh PIT oh pee15:34
de-factolol huh?15:34
dTalit's how I pronounce 'epitope'15:35
de-factooh yeah, now i got it :D15:35
de-factoafaik currently the BA.2.86.1 and JN.1 (EU) as well as HV.1 (US/CA) are on the rise15:37
de-factono idea how severe they are, but they seem to be the "new kid on the block" like many variants before them they take over the prevalence15:38
de-factohmm not good :(15:43
de-facto%title https://www.cidrap.umn.edu/covid-19/small-study-finds-brain-alterations-after-covid-omicron-infection15:43
Brainstormde-facto: From www.cidrap.umn.edu: Small study finds brain alterations after COVID Omicron infection | CIDRAP15:43
de-facto%title https://jamanetwork.com/journals/jamanetworkopen/fullarticle/281238715:43
Brainstormde-facto: From jamanetwork.com: Gray Matter Thickness and Subcortical Nuclear Volume in Men After SARS-CoV-2 Omicron Infection | Infectious Diseases | JAMA Network Open | JAMA Network15:43
de-factomaybe related?15:43
de-facto%title https://www.biorxiv.org/content/10.1101/2023.04.04.535604v115:43
Brainstormde-facto: From www.biorxiv.org: SARS-CoV-2 Spike Protein Accumulation in the Skull-Meninges-Brain Axis: Potential Implications for Long-Term Neurological Complications in post-COVID-19 | bioRxiv15:43
ublxthis is too funny/yikes not to share: https://www.theguardian.com/politics/2023/dec/04/dutch-media-report-claim-boris-johnson-planned-raid-on-vaccine-plant-in-202116:15
de-factoi wonder if some studies in the future may find out if the effects of the spike protein and the related potential (auto-) immune responses lead to behavioral changes on large scale e.g. not only anxiety but also cognitive dissonance and even aggressive behavior or lack of proper judgment associated with the inflammatory changes and also loss of gray matter in the brain16:42
de-facto%title https://www.medrxiv.org/content/10.1101/2022.06.02.22275916v1.full-text16:43
Brainstormde-facto: From www.medrxiv.org: Long COVID is associated with extensive in-vivo neuroinflammation on [18F]DPA-714 PET | medRxiv16:44
de-factoif it happens systematically on a large scale and synchronized (e.g. large parts of population/administration/government/CEOs etc) it could have a global impact16:45
de-factocurrently those inflammatory issues and long COVID problems probably are the most relevant subject of research given the large number of people affected, many probably fly under the radar of surveillance as in not appearing in stats due to them not being diagnosed properly or receiving medical treatment but rather trying to deal with the issues on their own instead16:47
de-factomy guess would be that COVID will be seen from a future point of view as one of the largest systematically (partially) disabling significant parts of the population events in modern medicine as we still dont really understand the full spectrum of problems associated with long lasting COVID symptoms even years after the infection16:50
de-factohence the urgency to invest more resources into the research of mitigating the disabling long term effects especially on an age group that carries the majority of the economic working force of a population16:51
de-facto%title https://www.nature.com/articles/s41586-022-04569-516:54
Brainstormde-facto: From www.nature.com: SARS-CoV-2 is associated with changes in brain structure in UK Biobank | Nature16:54
de-factoits known for a long time already16:55
BrainstormNew from New Scientist: Drug prevents fentanyl overdose for a month in monkeys: A single dose of a novel antibody medication can bind to fentanyl and prevent the opioid from triggering potentially life-threatening symptoms, research in monkeys suggests → https://www.newscientist.com/article/2406420-drug-prevents-fentanyl-overdose-for-a-month-in-monkeys/17:19
Timvdede-facto: I don't know which variant she got, she only did a RAT17:37
de-factoTimvde, do you know which vaccine she got?17:51
TimvdeNo idea, sorry17:52
BrainstormNew from Politico: Pfizer sues Hungary as pandemic court cases mount: The list of legal disputes around the EU’s COVID-19 vaccine purchases is growing. → https://www.politico.eu/article/pfizer-biontech-sues-hungary-pandemic-court-cases-mount-covid-19/17:57
BrainstormNew from Eric Topol on Mastodon: (news): US Covid hospitalizations are on the rise, now  >20,000 new admits/week, and this wave is just getting started as the JN.1 variant becomes dominant and wastewater levels surging in the Midwest with other regions to follow. → https://mstdn.social/@erictopol/11152889575199648118:07
de-factoTimvde, how bad is it for her?18:14
de-factothe COVID infection18:14
BrainstormNew from r/Coronavirus: Coronavirus: The lingering symptoms of post-COVID-19 condition (long-COVID): a prospective cohort study → https://old.reddit.com/r/Coronavirus/comments/18bh3gg/the_lingering_symptoms_of_postcovid19_condition/18:26
BrainstormNew from Marc Veldhoen on Mastodon: (news): This work underscores the potential application of tissue-specific, in this case, lung-selective, mRNA. The protein of choice is antibodies that help in the prevention and treatment of infections caused by respiratory pathogens. → https://mastodon.online/@marc_veld/11152975935980993921:50
BrainstormNew from Marc Veldhoen on Mastodon: (news): "COVID-19 vaccination did not increase the risk of unexplained sudden death among young adults in India. Past COVID-19 hospitalization, family history of sudden death and certain lifestyle behaviors increased the likelihood of unexplained sudden death." → https://mastodon.online/@marc_veld/11152979310995427721:59
Timvdede-facto: bad flu23:34
TimvdeFever, being exhausted to the point of lying in bed most of the day, aching muscles23:35
de-factodoes she drink enough? its extremely important23:36
de-factofor how long does she have it?23:37
TimvdeAfaik first mild symptoms over the weekend, everything I just said on Monday23:38

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